Allergic reactions to Clopidogrel can be treated with steroids and antihistamines

A clinical study of cardiac patients who suffered an allergic reaction to the widely-prescribed drug Clopidogrel ( Plavix ), found ...

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Anti–TNF-alpha agents may be associated with increased risk for herpes zoster

Anti-tumor necrosis factor alpha ( TNF-alpha ) antibodies for the treatment of rheumatoid arthritis appears to be associated with an ...

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Clopidogrel plus Aspirin reduces myocardial infarction risk in patients with acute coronary syndrome

In order to better prevent blood clots, Clopidogrel ( Plavix ) can be prescribed to patients with acute ischaemia of ...

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Proton pump inhibitors interfere with Clopidogrel

The anti-clotting action of the medication Clopidogrel ( Plavix ) can be compromised by common drugs for the treatment of ...

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Cladribine in patients with relapsing-remitting multiple sclerosis: two-year data

Merck KGaA announced results of the two-year ( 96-week ) placebo-controlled CLARITY Phase III trial using Cladribine tablets to treat ...

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Antiepileptics associated with decreased bone mineral density

The antiepileptic drugs Carbamazepine, Phenytoin, Primidone, and Phenobarbital are known to cause osteomalacia, and the product information for healthcare professionals for ...

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Methylthioninium in high intravenous doses should be avoided for patients being treated with serotonergic antidepressants

Methylthioninium chloride is approved for the management of drug-induced methaemoglobinaemia in adults. It is also used for other purposes, but ...

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Ceftriaxone and Calcium-containing products may be used concomitantly in patients greater than 28 days of age

The full prescribing information for Ceftriaxone ( Rocephin and its generics ) has been changed. This information updates a previous Alert ...

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FDA has approved Simponi for rheumatoid arthritis, psoriatic arthritis, and ankylosing spondylitis

The FDA ( Food and Drug Administration ) approved Simponi ( Golimumab ), a monthly treatment for adults with moderate-to-severe ...

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Genentech: voluntary withdrawal of Raptiva from the U.S. market

Genentech, the manufacturer of the psoriasis drug Raptiva ( Efalizumab ), announced that it has begun a voluntary, phased withdrawal ...

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A case of progressive multifocal leukoencephalopathy in a Raptiva patient

Genentech announced that the company has issued a Dear Healthcare Provider letter to inform potential prescribers of a case of ...

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Sorafenib targets acute myeloid leukemia driven by mutant FLT3 gene

A drug used to treat kidney cancer also targets a genetic mutation active in about one third of patients with ...

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Sorafenib: older renal cancer patients appear to benefit from treatment

Older and younger patients with renal cancer derive similar benefit from Sorafenib ( Nexavar ) therapy and tolerate the drug ...

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Genetic study sheds new light on lung adenocarcinoma

A multi-institution team, funded by the National Human Genome Research Institute ( NHGRI ) of the National Institutes of Health ...

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BRAF mutations in colorectal cancer cause resistance to anti-EGFR therapy

European Researchers have found that metastatic colorectal cancer patients with a mutation in the BRAF gene do not respond to ...

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Cancer: new biomarkers can predict response to treatments

Genetic variations ensure that no two people are exactly alike, nor are their cancers. Researchers now have the tools and ...

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Everolimus prolongs progression-free survival in patients with metastatic kidney cancer who have failed on other treatments

Treatment with Everolimus ( Certican ) prolongs progression-free survival relative to placebo in patients with metastatic kidney cancer ( renal ...

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Imatinib and Sunitinib prevent and reverse type 1 diabetes

The drugs, Imatinib ( Glivec / Gleevec ) and Sunitinib ( Sutent ), were found to put type 1 diabetes ...

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Consolidation therapy following chemoimmunotherapy in B-cell chronic lymphocytic leukaemia: infection-related deaths reported with the use of MabCampath

Bayer HealthCare and Genzyme, in collaboration with Health Canada, informed of important safety information regarding the use of MabCampath ( ...

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FDA has approved Degarelix for patients with advanced prostate cancer

The FDA ( Food and Drug Administration ) has approved the injectable drug Degarelix, the first new drug in several ...

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Suicidal behavior and ideation linked to antiepileptic drugs

The FDA ( Food and Drug Administration ) has completed its analysis of reports of suicidality ( suicidal behavior or ...

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DECREASE III trial: Fluvastatin XL is associated with improved cardiac outcome after major vascular surgery

Annually, approximately 40 million people undergo noncardiac surgery in the European Union. Of these patients approximately 400,000 ( 1% ) ...

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Men who take Acetylsalicylic acid have significantly lower PSA levels

The use of Acetylsalicylic acid ( Aspirin ) and other non-steroidal anti-inflammatory drugs ( NSAIDs ) is significantly associated with ...

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Acetylsalicylic acid does not prevent myocardial infarctions in patients with diabetes

Taking regular Acetylsalicylic acid ( Aspirin ) and antioxidant supplements does not prevent myocardial infarctions even in high risk groups ...

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Chlorthalidone reduces risk for a type of heart failure that is more common among women

New research by The University of Texas School of Public Health has shown that a diuretic is particularly effective at ...

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Citalopram may prevent depression in patients with head and neck cancer

Taking the antidepressant Citalopram ( Celexa, Seropram ) before beginning treatment for head and neck cancer may help prevent depression ...

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Multiple sclerosis: Rituximab shows promise

A drug therapy currently used to treat non-Hodgkin’s lymphoma and rheumatoid arthritis had a significant effect in treating the most ...

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Patient with systemic mastocytosis responds to Imatinib

A rare disorder caused by an excess of two types of immune cells, the mast cell found in various tissues ...

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Risk of psychiatric side effects is approximately doubled in patients taking Acomplia

The European Medicines Agency ( EMEA ) has completed a review of Acomplia ( Rimonabant ) at the request of ...

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Bowel cleansing: oral Sodium Phosphate products associated with risk of acute kidney injury

The FDA ( Food and Drug Administration ) has announced that it will add a Boxed Warning to the prescription ...

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Use of conventional antipsychotics in elderly patients with dementia

The European Medicines Agency ( EMEA ) has completed a review of the evidence available on the safety of conventional ...

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FDA has approved Toviaz to treat overactive bladder

The FDA ( Food and Drug Administration ) has approved a new drug to help patients suffering from overactive bladder ...

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FDA has approved Banzel to treat seizures associated with Lennox-Gastaut syndrome

The FDA ( Food and Drug Administration ) has approved a new drug, Banzel ( Rufinamide ), for use as ...

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Influenza: safety information on Tamiflu

Tamiflu ( Oseltamivir ) is indicated for the treatment of uncomplicated acute illness due to influenza infection in patients 1 ...

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Human papillomavirus vaccine: Gardasil

Gardasil is a vaccine. It is a suspension for injection that contains purified L1 proteins for 4 types of the ...

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