Women who have an infant that dies of sudden infant death syndrome ( SIDS ) have an increased risk of preterm delivery and complications in subsequent pregnancies.

SIDS is the most important single cause of infant mortality in the developed world.

Gordon Smith, at the University of Cambridge, UK, and colleagues investigated whether women whose infants die from SIDS would be more likely to have complications in their future pregnancies.

They looked at data on maternity-hospital discharge and infant deaths for over 258,000 women who had consecutive births in Scotland between 1995 and 2001.

The researchers found that women whose previous infant died were two to three times more likely to deliver an infant who was small for their gestational age, and two to three times more likely to have a preterm delivery.

Women who had infants which were small for their age or delivered preterm had a two-fold increased risk of SIDS occurring in their subsequent births.
The investigators found that the association persisted even after they took into account other possible risk factors for SIDS, such as smoking status, maternal age, and marital status.

"Our findings suggest a mechanism that would predispose a women to recurrent cases of SIDS and provide direct evidence that the risk of SIDS after a given birth is not statistically independent of whether the previous infants died," Smith said.

Source: The Lancet, 2005


XagenaMedicine2005