Researchers at Mayo Clinic have found that people with rheumatoid arthritis are no more likely to have hearing loss than other members of the general population.
The finding is contrary to previous study results that linked the disease to elevated risk of hearing problems.

" This is very good news for rheumatoid arthritis patients," says Eric Matteson, at Mayo Clinic and senior study researcher. " Patients with rheumatoid arthritis actually have preserved hearing and are no more susceptible to hearing loss than those who do not have the disease; there is no measurable difference with standard testing. This was surprising. I expected to see more hearing loss in rheumatoid arthritis patients."

The study included 29 patients ages 40 to 69 who had rheumatoid arthritis for more than five years, categorized by decades of age. The researchers compared them to 30 participants of the same gender and age categories who did not have rheumatoid arthritis.
All participants had comprehensive hearing tests and questionnaires to measure hearing and dizziness handicaps and assess their overall health.
Seventeen of 29 patients with rheumatoid arthritis had abnormal hearing for at least one sound frequency, as did 14 of 30 of those without rheumatoid arthritis.

Matteson notes, however, that the findings do not mean that hearing loss is never related to rheumatoid arthritis. " Hearing loss can be a symptom of rheumatoid arthritis, but it doesn't seem to be more of a problem than in the general population," he says.

The researchers found that though no objective difference was detected in comprehensive hearing evaluations of rheumatoid arthritis patients compared to those without the disease, the rheumatoid arthritis patients were more likely to perceive that they had hearing problems. This phenomenon was most pronounced in those who had more severe rheumatoid arthritis and had disabilities due to the disease.

Among the rheumatoid arthritis patients who had hearing loss, most often the loss was partial and due to nerve problems in the inner ear ( sensorineural ). The cause of this loss is uncertain, but may be due to factors such as noise exposure.
In addition, the hearing loss may be related to an autoimmune attack in which the immune system attacks the cochlea, the inner ear cavity containing hair cells and the nerves which connect the cochlea to the brain.
The researchers also noted a possible link between the hearing loss and rheumatoid arthritis medications, as patients who took Hydroxychloroquine were somewhat more likely to have hearing problems than other study participants.

Source: Mayo Clinic, 2006


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