Long-term survival and risk of vascular events after TIA or minor ischemic stroke


A study found that patients who have had a minor stroke have a 43% chance of another stroke or vascular event within 10-years.

Ale Algra, at the University Medical Centre, Utrecht ( Netherlands ), and colleagues assessed the survival status and occurrence of vascular events in over 2400 patients recruited from 24 hospitals in the Netherlands.

They found that, roughly 10 years after a presentation of TIA or minor ischaemic stroke, about 60% of patients had died and 54% had experienced at least one new vascular event.
Event-free survival after 10 years was 48%.
The risk of a vascular event was highest shortly after the ischaemic event, reached its lowest point at about 3 years, and gradually rose afterwards.

Algra concludes: “ Throughout our study, the risk of mortality gradually rose, whereas that of stroke fell in the first three years and remained constant thereafter . . . These findings imply that further improvement can still be established on longterm secondary prevention of vascular disease in patients with cerebral ischaemia.”

In an accompanying comment Graeme Hankey of the Royal Perth Hospital ( Australia ) states: “ The implications of van Wijk and colleagues’ study, which can confidently be generalised to other hospital-referred patients, are that patients with TIA and minor ischaemic stroke should be repeatedly assessed, because their risk can change, treated to prevent cerebrovascular and cardiovascular events, and treated long-term.”

Source: The lancet, 2005


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