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Iodine seed-marking protocol for response-guided axillary treatment after systemic therapy for node-positive breast cancer

Most patients with clinically node-positive (cN+) breast cancer receive primary systemic treatment (PST) followed by axillary lymph node dissection (ALND) ...
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Importance of specific immunologic biomarkers in determining irCRS severity, predicting outcomes, and distinguishing between immune-related hemophagocytic lymphohistiocytosis, immune-related cytokine release syndrome, and sepsis

The advent of immune checkpoint inhibitors (ICIs) has marked a pivotal turning point in the landscape of cancer treatment, with ...
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Hormone therapy use and young-onset breast cancer: a pooled analysis of prospective cohorts included in the Premenopausal Breast Cancer Collaborative Group

Oestrogen plus progestin hormone therapy is an established risk factor for breast cancer in postmenopausal women. It was examined the ...
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Overall efficacy and safety of Olanzapine 5 mg added to triplet antiemetics for an anthracycline-containing regimen in patients with breast cancer

The addition of 10 mg Olanzapine to the standard triplet antiemetic therapy has shown superiority in controlling chemotherapy-induced nausea and ...
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Loqtorzi based on Toripalimab associated with chemotherapy for the first-line treatment of metastatic or recurrent, locally advanced nasopharyngeal carcinoma. FDA approved

The Food and Drug Administration ( FDA ) has approved Loqtorzi ( Toripalimab-tpzi; Toripalimab ) with Cisplatin and Gemcitabine for ...
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Breyanzi, a CAR T cell therapy, for relapsed / refractory diffuse large B-cell lymphoma, primary mediastinal large B-cell lymphoma, and follicular lymphoma grade 3B: approved in European Union

The European Commission has approved Breyanzi ( Lisocabtagene maraleucel; Liso-cel ) for the treatment of adult patients with relapsed or ...
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Cancer: innovations in liquid biopsies

From using fluid in the lungs to better understand the potential of immunotherapy treatments in lung cancer, to tracking circulating ...
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Elevated blood pressure in young adults associated with middle-age heart issues

Young adults who had blood pressure that was elevated but still within normal range for long periods of time were ...
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Peyronie's disease: surgical therapy remains the gold standard for patients in the chronic phase

Peyronie's disease is an under-diagnosed condition with prevalence in the male population as high as 9%. It is a localized ...
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In patients with inflammatory bowel disease sexual function among may be impaired

Inflammatory bowel diseases ( IBD ) is a group of chronic, debilitating inflammatory intestinal conditions. The aim of a review ...
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Folliculitis decalvans: oral Isotretinoin as the most effective treatment

Folliculitis decalvans leads to scarring alopecia through inflammatory destruction of the hair follicle. Currently, antibiotics are most commonly used to ...
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Normal bone mass and normocalcemia in adulthood despite homozygous vitamin D receptor mutations

Adding to the debate around vitamin D's effects on skeletal health, researchers have reported the long-term follow-up of two patients ...
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Atrial fibrillation: new analyses highlight undertreatment of patients at high risk of stroke

Two analyses from the GLORIA-AF Registry Program examining the use of anticoagulant treatments for stroke prevention in patients with atrial ...
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Penile fracture: immediate treatment leads to better long-term results, with a lower incidence of erectile dysfunction and penile curvature

The objective of a study was to review the cases of patients with suspected penile fracture and asses erectile and ...
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Informed decision making about mammography screening for breast cancer

A) Mammography is not a perfect screening test, and understanding of its benefits and harms is incomplete Some cancers will be ...
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Pediatric migraine: Ibuprofen and Paracetamol are widely used to control pain

Migraine is a common disorder and a frequent cause of medical consultation in children. Many childhood episodic syndromes have been ...
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Vitamin D, female fertility, polycystic ovary syndrome, endometriosis

Apart from the well known effects of vitamin D on maintaining calcium homeostasis and promoting bone mineralization, there is some ...
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Pulmonary hypertension due to COPD: long-term effect of vasodilator therapy

Pulmonary hypertension ( PH ) due to COPD ( chronic obstructive pulmonary disease ) has dismal prognosis. Researchers reviewed the ...
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Genetic variants influence responses to statins

Statins are widely prescribed to patients and have been shown to lower LDL cholesterol levels by up to 55%, making ...
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Risky behaviors of gambling associated with sex

Late adolescence is a period when many youth become involved in high-risk behaviors with adverse consequences. Researchers at the Mailman ...
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Vitamin D deficiency linked to diabetes mellitus type 1

A study led by researchers from the University of California, San Diego ( UCSD ) School of Medicine has found ...
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Catheter ablation for atrial fibrillation: results from Atrial Fibrillation Ablation Pilot Study

Catheter ablation for atrial fibrillation ( Afib ) is safe and suppresses arrhythmia recurrences in 74% of patients after a ...
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FDA: alert on potential dangers of treatment for chronic cerebrospinal venous insufficiency

The FDA ( Food and Drug Administration ) has alerted health care professionals and patients about injuries and death associated ...
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Bariatric surgery among older, high-risk patients not associated with reduced mortality

The use of bariatric surgery among older, severely obese patients was not associated with a decreased risk of death, according ...
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IARC: radiofrequency electromagnetic fields as possibly carcinogenic to humans

The WHO / International Agency for Research on Cancer ( IARC ) has classified radiofrequency electromagnetic fields as possibly carcinogenic ...
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Chronic cerebrospinal venous insufficiency appears to be more common in people with multiple sclerosis

Chronic cerebrospinal venous insufficiency ( CCSVI ) appears to be more common in people with multiple sclerosis than in people ...
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Type 2 diabetes mellitus: fracture prediction methods may be useful

Use of established fracture prediction methods in older patients with type 2 diabetes mellitus found that scores from these methods ...
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Mutations in genes PU.1 and Spi-B causes acute lymphoblastic leukemia

Researchers at The University of Western Ontario have identified genes that may be important for preventing childhood leukemia. Acute lymphoblastic ...
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High breast density, no lobular involution increase breast cancer risk

Women with dense breasts and no lobular involution were at a higher risk for developing breast cancer than those with ...
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Radiation exposure: risk of cancer in middle age may be higher than previously estimated

Contrary to common assumptions, the risk of cancer associated with radiation exposure in middle age may not be lower than ...
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