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Serious adverse reactions to smallpox vaccine appear to be limited

There was a low rate of life-threatening adverse reactions to the smallpox vaccine administered to potential first responders to a ...
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Fructose linked to metabolic syndrome

Researchers from University of Florida ( UF ) have identified one possible reason for rising obesity rates, and it all ...
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Pancreatic cancer: new treatment reduces the size of tumors and lowers the risk of local recurrence of the disease

A new treatment for pancreatic cancer developed by researchers of Norris Cotton Cancer Center at Dartmouth-Hitchcock Medical Center substantially reduces ...
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Colon cancer: more patients are receiving chemotherapy after surgery, with increase in survival rate

More patients with stage III colon cancer are receiving chemotherapy after surgery, with an associated significant increase in 5-year survival. The ...
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Pneumonia hospitalization rates on the rise for older adults

Hospitalization rates for pneumonia have increased substantially for U.S. adults 65 to 84 years of age. Pneumonia is among the top ...
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Children with heart defects benefit from exercise

A pilot study indicates that many children with serious congenital heart disease, who are typically urged to restrict their activity, ...
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Modified Atkins diet may be effective in controlling seizures

Researchers at Johns Hopkins Children's Center have found that a modified version of a popular low-carbohydrate, high-fat diet is nearly ...
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Teen weight control behavior may reflect mothers' attitudes on weight

A study, published in the Archives of Pediatrics & Adolescent Medicine, has found that teenagers are more likely to think ...
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Psychosocial disability fluctuates in parallel with bipolar symptom changes

With every increase or decrease in depressive symptom severity, there is a corresponding significant and stepwise increase or decrease in ...
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Biochemical connection between hepatitis C virus and liver cancer identified

Researchers at the University of Texas Medical Branch at Galveston ( UTMB ) have identified a key biochemical connection between ...
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Autistic children's brains grow larger during first years of development

A study by researchers at the University of North Carolina at Chapel Hill and Duke University found that, by age ...
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Chemotherapy after surgery extends survival for patients with advanced endometrial cancer

A study has shown for the first time that giving two chemotherapy drugs to women with advanced endometrial cancer after ...
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Uncontrolled high blood pressure linked to more cognitive problems in elderly patients

People with high blood pressure and their doctors have a new reason to work at controlling this common but high-risk ...
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Tuberculosis, a risk for patients receiving HAART therapy

People taking highly active antiretroviral therapy ( HAART ) for HIV infection remain susceptible to tuberculosis, though the risk is ...
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Eye movement test may help to identify children with fetal alcohol spectrum disorder

A simple test that measures eye movement may help to identify children with Fetal Alcohol Spectrum Disorder ( FASD ) ...
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Diabetes: differences in the skin allow to detect ulcerative foot disease before it develops

Foot ulcerations are one of the most serious complications of diabetes, resulting in more than 80,000 lower-leg amputations each year ...
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Exercise adds years to life and improves quality of life

Researchers at the University of Illinois ( UI ) at Urbana-Champaign who study the effects of exercise on aging point ...
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Meditation associated with increased grey matter in the brain

Meditation is known to alter resting brain patterns, suggesting long lasting brain changes. A new study by researchers from Yale, Harvard, ...
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Prostate cancer: PSA kinetics can predict disease progression and likelihood of death after radical prostatectomy

Researchers at Mayo Clinic reported that prostate specific antigen ( PSA ) kinetics, both velocity and doubling time, can be ...
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Risks of taking sedatives for insomnia in older people may be greater than the benefits

For older people, the risks outweigh the benefits of taking sleeping pills and other sedatives, say researchers in a study ...
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Ink4c and Ptch1 genes collaborate to suppress medulloblastoma

The Ink4c and Ptch1 genes collaborate to suppress the development of medulloblastoma, the most common pediatric brain tumor, according to ...
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Genes involved in biofilms

The researcher Alejandro Toledo Arana at University of Navarra has identified two new genes that operate as regulators in the ...
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Mouse nose detects most pheromones governing reproduction

Researchers at Harvard University have found strong signs that the pheromones driving reproduction and fertility in mice are detected primarily ...
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Bird flu virus triggers worse inflammation in human lung cells than human flu viruses

Researchers might have identified one of the reasons why the bird flu virus H5N1 is so deadly to humans. A study ...
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Molecular identification of bacteria associated with bacterial vaginosis

Findings reported in the New England Journal of Medicine ( NEJM ) highlight promising findings from two Seattle-based researchers on ...
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No evidence that cholesterol drugs lower melanoma risk

No clear evidence exists that some widely-prescribed cholesterol-lowering drugs can decrease the risk of melanoma, a deadly and malignant skin ...
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Nine percent of children may outgrow their tree nut allergies

Approximately 9% of children with an allergy to tree nuts will outgrow their allergy, including children who have previously experienced ...
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Chlamydia pneumoniae present in eyes with wet age-related macular degeneration

Researchers at the Massachusetts Eye and Ear Infirmary ( MEEI ) have found that Chlamydia pneumoniae, a bacterium linked to ...
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Brainstem blocks pain to protect key behaviors

Certain behaviors, such as eating, drinking and urinating, are so crucial to survival that the brains of all vertebrates contain ...
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Resetting epigenetic code could aid patients with systemic lupus erythematosus

Researchers at Wake Forest University School of Medicine and the University of Virginia hope to reset part of the "epigenetic ...
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Nanoparticle-aptamer bioconjugates as targeted drug delivery

Results from researchers at Harvard Medical School and Massachusetts Institute of Technology ( MIT ) have shown for the first ...
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Anti-inflammatory drugs may cut risk of esophageal cancer in people with Barrett's esophagus

Aspirin and other nonsteroidal anti-inflammatory drugs ( NSAIDs ), such as Ibuprofen, may significantly reduce the risk of esophageal cancer ...
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Common viruses may cause cancer

In some cases, the fusion of human cells is a normal process that leads, for instance, to the formation of ...
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RNA splicing occurs in nerve-cell dendrites

Researchers at the University of Pennsylvania School of Medicine have discovered that nerve-cell dendrites have the capacity to splice messenger ...
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Sleeping sickness parasite shows how cells divide their insides

Researchers at Yale Univeristy have brought to light a mechanism that regulates the way an internal organelle, the Golgi apparatus, ...
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MRI for early diagnosis of schizophrenia

Researchers may have discovered a new way that may assist in the early diagnosis of schizophrenia by utilizing MRI ( ...
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Antisocial behavior in children associated with gene variant and environmental risk factors

For children with attention deficit hyperactivity disorder ( ADHD ), possessing a variant of a gene involved in brain signaling ...
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Dendritic cells offer new therapeutic target for drugs to treat multiple sclerosis

Researchers at the Johns Hopkins Kimmel Cancer Center have found that a gene pathway linked to a deadly form of ...
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New antibody shows promise as cure for anthrax

A new anthrax antibody engineered by researchers at The University of Texas at Austin protects and defends against inhalation anthrax ...
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Slight increased risk of major birth defects associated with IVF

A study, conducted by researchers at the University of Iowa ( UI ), found that children conceived through in vitro ...
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Gene for debilitating vitamin B12 disease identified

Researchers at the MUHC and McGill University have identified a gene responsible for a disease that impairs the body's ability ...
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High-resolution computed tomography reveals asthmatic risk long after cat allergen exposure

Researchers have shown that cat allergens can impair lung function in people with asthma for up to 22 hours after ...
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Acetaminophen poisoning, the most common cause of acute liver failure in the United States

"Acetaminophen poisoning has become the most common cause of acute liver failure in the United States," report the authors of ...
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MicroRNAs have shaped the evolution of the majority of mammalian genes

Researchers in the lab of David Bartel at Whitehead Institute have found that a class of small RNAs called microRNAs ...
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Type of childhood cancer and treatment received linked to physical problems later in life

A University of Minnesota Cancer Center study is the first to show how the prevalence of some physical impairments that ...
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Emergency bypass surgery on angioplasty patients drops 90 percent

A study, published in the Journal of the American College of Cardiology, has shown when life-threatening problems occur during angioplasty ...
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After a stroke, aldosterone helps neurons survive

Despite better management of blood pressure – the number-one risk factor for strokes – stroke incidence is not declining and ...
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Some patients who receive an appropriate level of Morphine live a little longer

A report written by an OHSU physician with more than a half century of medical experience contradicts both public and ...
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MMP2 gene is essential for the growth of new arteries

Researchers at the San Francisco VA Medical Center have uncovered part of the genetic mechanism that causes new arteries to ...
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Young women who smoke higher risk of breask cancer

A study of postmenopausal women supports the hypothesis that women who smoke cigarettes before first full-term pregnancy have a 20 ...
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Liver transplant may not be indicated for cystic fibrosis patients with bleeding complication

A study on patients with cystic fibrosis who have had abnormal bleeding from ruptured blood vessels in the esophagus ( ...
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Betamethasone given to pregnant women can affect brains and behaviour of their grandchildren

A study in guinea pigs suggests that a drug commonly given to pregnant women to help their babies mature enough ...
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Insulin levels drop with progression of Alzheimer's disease

Researchers at Rhode Island Hospital and Brown Medical School have discovered that insulin and its receptors drop significantly in the ...
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Rapid screen-and-treat methods for cervical cancer significantly reduce cancer precursor lesions

A study led by researchers from Columbia University Medical Center demonstrates the safety and efficacy of two low-tech diagnostic tools ...
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Scar tissue in heart predicts risk of fatal arrhythmias

Researchers at Johns Hopkins have found that people whose muscle wall thickness contained more than 25 percent scar tissue were ...
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Travelers can avoid jet lag by resetting their body clocks

A simple, a single light box and the over-the-counter drug Melatonin, allows travelers to avoid jet lag by resetting their ...
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Interferon with Ribavirin is safe and effective for children with chronic hepatitis C

Nearly half of 118 children with chronic Hepatitis C virus ( HCV ) treated with a combination of Interferon-alpha-2b ( ...
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Ritalin shows promise in the treatment of hyperactivity associated with autism-related disorders

A study published in the Archives of General Psychiatry, found that medication commonly used to treat attention-deficit hyperactivity disorder ( ...
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Lovastatin reverses learning and attention deficits in a mouse model of neurofibromatosis type I

Researchers have reported evidence that a statin, Lovastatin ( Mevacor ), already shown to be safe for use in humans ...
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Fibrodysplasia ossificans progressiva: medical misdiagnosis

A research study shows how common a medical misdiagnosis can be and how severely it can exacerbate a disease. Focusing ...
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Adolescents who watch smoking in movies are more likely to try smoking

The first national study to look at the connection between smoking in movies and smoking initiation among adolescents shows that ...
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Leber congenital amaurosis: successful tests of new treatments in mice

A team led by Krzysztof Palczewski, at the Case Western Reserve University School of Medicine, has taken the first steps ...
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Causes of primary biliary cirrhosis

A case-control study of more than 2000 people has identified a number of factors that may induce primary biliary cirrhosis ...
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MetAP2, a new target in neurofibromatosis 1

Researchers studying a mouse model of neurofibromatosis 1 ( NF1 ), a genetic condition that causes childhood brain tumors, have ...
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Neuron plasticity linked to learning and memory

Neurons experience large-scale changes across their dendrites during learning, say neuroscientists at The University of Texas at Austin. The research, published ...
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Diabetic blacks have less coronary artery disease than diabetic whites

Researchers at Wake Forest University Baptist Medical Center found that diabetic black men have dramatically lower amounts of atherosclerosis, or ...
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Lung scarring diseases linked to genes and smoking

A research has shown that idiopathic interstitial pneumonia ( IIP ), a group of potentially fatal disorders that affects the ...
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Chernobyl legacy sheds light on link between thyroid cancer and radiation exposure

Study results have provided further valuable insights into certain genetic mutations which occur in childhood thyroid tumours and their link ...
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Radical prostatectomy is fairly safe for older men

Radical prostatectomy may be a safe option for the treatment of prostate cancer in otherwise healthy men up to age ...
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CDKN2A mutations have a modest impact on the incidence of melanoma

People who carry a mutation in the melanoma susceptibility gene CDKN2A have a much lower risk of melanoma than has ...
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Notch signaling molecule important in type 2 immunity

Defects in immune system cells called T helper cells may lead to diseases characterized by a faulty inflammatory response such ...
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Variation in dopamine receptor gene is associated with hypertension

In a study, published in the American Journal of Hypertension, researchers at the University of Michigan ( U-M ) have ...
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Retinoblastoma: combination therapy with Topotecan and Carboplatin

Researchers at St. Jude Children's Research Hospital have demonstrated in laboratory studies a new treatment for the pediatric eye cancer, ...
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FDA has approved Revlimid for the treatment of patients with myelodysplastic syndrome linked to deletion 5q

The FDA ( U.S. Food and Drug Administration ) has approved the drug Revlimid ( Lenalidomide ) for the treatment ...
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FDA: Femara as initial therapy for treatment of postmenopausal women with early breast cancer after surgery

The US regulatory has approved Femara ( Letrozole), a once-a-day oral aromatase inhibitor, in a new indication as a treatment ...
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Analysis of severe adverse events related to the use of Mifepristone as an abortifacient

A systematic analysis of the FDA's Adverse Event Reporting System ( AERS ) has been performed to assess morbidity and ...
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Glioblastoma multiforme: a new therapy based on the detection of EGFR

Researchers have devised a strategy to treat tumors by selectively targeting and killing the malignant cells. A new preclinical study, published ...
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Vitamin B1 deficiency after bariatric surgery

A case study, published in the journal Neurology, has shown that deficiency in vitamin B1 can be a serious complication ...
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Secondary prevention after myocardial infarction: high-dose Atorvastatin not better than usual-dose Simvastatin

Intensive lipid lowering with Atorvastatin 80 mg did not result in a significant reduction in the primary end point of ...
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Femara better than Tamoxifen in early breast cancer

A trial, published in the New England Journal of Medicine showed that Femara ( Letrozole ) demonstrated a significant ...
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FDA approves Tamiflu for prevention of influenza in children under age 12

The FDA ( U.S. Food & Drug Administration ) approved the use of Tamiflu ( Oseltamivir ) for prevention of ...
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Neuron growth in adult brain found

A researcher at MIT's Picower Institute for Learning and Memory reports in the Public Library of Science ( PloS ) ...
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Muscular dystrophy: gene therapy technique to permanently produce dystrophin

A new gene therapy technique that has shown promise in skin disease and hemophilia might one day be useful for ...
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Childhood infections shorten life

Records from four European countries show that, on average, survivors of generations with rampant childhood infection - measured by cohort ...
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Vitamin D appears to lower the risk of developing cancers

Researchers at the Moores Cancer Center at the University of California, San Diego ( UCSD ), …taking 1,000 international units ...
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Higher cardiovascular risk if siblings have cardiovascular disease

A study, published in the JAMA, found that middle-aged adults who have a sibling with cardiovascular disease ( CVD ) ...
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Amiodarone reduces risk of atrial tachyarrhythmias after cardiac surgery

Use of the antiarrhythmic agent Amiodarone ( Cordarone ) is associated with one-half the incidence of atrial tachyarrhythmias following cardiac ...
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Dietary intake of antioxidants linked to reduced risk of age-related macular degeneration

A study, published in the JAMA, has found that a diet with a high intake of beta carotene, vitamins C ...
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Efficacy of Remicade in patients with ulcerative colitis

Patients with moderate-to-severe active ulcerative colitis treated with Infliximab ( Remicade ) at weeks 0, 2, and 6 and every ...
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Cervical cancer screening failure linked to poverty

African-American women living in communities with high poverty rates are less likely to be screened for cervical cancer, even after ...
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Sickle cell disease corrected in human models using stem cell-based gene therapy

In a study, published in the Nature Biotechnology, researchers led by a team of scientists at Memorial Sloan-Kettering Cancer Center ...
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Food insecurity impairs academic development of children

A longitudinal Cornell University study found when young school-age children do not always have enough to eat, their academic development ...
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Role of RNA editing in gene control

For many years, researchers thought gene activity was relatively straightforward: genes were transcribed into messenger RNA, which was processed and ...
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B cell lymphomas and other EBV-associated illnesses: role of Epstein-Barr virus protein, EBNA3C

Researchers at the University of Pennsylvania School of Medicine identified a link between a critical cancer pathway and an Epstein-Barr ...
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Role of microRNA in papillary thyroid cancer

The presence of only five tiny strands of RNA is enough to clearly distinguish cancerous thyroid tissue from otherwise normal ...
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Short telomeres linked to dyskeratosis congenita

A Johns Hopkins geneticist and her team have discovered a critical link between the health of stem cells and the ...
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Excessive doses of antithrombotic therapy in patients with acute coronary syndromes

A prospective observational analysis, coordinated by the DCRI ( Duke Clinical Research Institute ), in 387 US hospitals of 30,136 ...
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Steps required to integrate new neurons into adult brain discovered

In experiments with mice, researchers from Johns Hopkins' Institute for Cell Engineering ( ICE ) have discovered the steps required ...
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TGF-beta gene is necessary for proper development of frontal bones

Craniofacial researchers have developed an animal model that explains how skull malformations occur and how they might be prevented. Birth ...
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Safety of oral contraceptives in women with lupus erythematosus

A study, funded by the National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS), a part of the National ...
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