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Medicine News

Medicine - Xagena Medical News

Newsletter Xagena

Aggiornamento in Medicina

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Cystic fibrosis: stopping inhaled corticosteroid use causes no problems

In comparison to cystic fibrosis patients who regularly use inhaled corticosteroid, those who did not use these drugs for six ...
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Role of gene mutations causing lupus in mice identified

In two related studies, researchers at the University of Texas ( UT ) Southwestern Medical Center have pinpointed defective genes ...
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Exenatide reduces blood glucose levels when added to patients using a thiazolidinedione

A study showed that Exenatide ( Byetta ) injection lowered blood glucose levels for people with type 2 diabetes who ...
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Rosuvastatin plus diet in hypercholesterolemic adults unable to tolerate other statins

Patients with high levels of low-density lipoprotein cholesterol ( LDL-C ) might not tolerate HMG-CoA reductase inhibitors, also known ...
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Mechanism for neurodenegerative diseases linked to transport proteins

Hampering the transport of proteins within cells may underlie several adult-onset neurodegenerative diseases, such as Huntington's, amyotrophic lateral sclerosis ( ...
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HBZ protein enhances the ability of HTLV-1 to establish a persistent infection

A study has examined the function of a protein called HBZ, which is made by the human T cell leukemia ...
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ACC/AHA/ESC 2006 Guidelines - Pharmacological rate control during atrial fibrillation

For patients with symptomatic atrial fibrillation lasting many weeks, initial therapy may be anticoagulation and rate control while the long-term ...
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Exubera's long-term efficacy and safety in adults with type 1 or type 2 diabetes

Results from two ongoing studies showed adults with type 1 or type 2 diabetes treated with Exubera, a rapid-acting, dry ...
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Trans fat leads to weight gain even on same total calories

A research, in animal model, at Wake Forest University School of Medicine, has shown that the "apple" body shape that ...
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Inhibition of LDH-A may represent a rational and safe strategy for treatment of cancer

Although researchers have known for nearly 90 years that cancer cells commonly display altered glucose metabolism, the molecular significance of ...
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Peripheral neuropathic pain: Lyrica is not recommended for use within NHS Scotland

The Scottish Medicines Consortium ( SMC ) has advised NHS ( National Health Service ) Boards and Area Drug and ...
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Metastatic colorectal cancer - NICE: insufficient evidence to recommend Avastin and Erbitux

The Appraisal Committee has prepared a Final Appraisal Determination on the use of Avastin and Erbitux in metastatic colorectal cancer ...
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HIV infection, Prezista, a new protease inhibitor for patients who do not respond to existing drugs, approved

The FDA ( Food and Drug Administration ) approved Prezista ( Darunavir ), a new drug for adults whose infection ...
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Inhibition of TWEAK may provide a new approach to rheumatoid arthritis therapy

Researchers at Biogen Idec reported in the Journal of Immunology that activation of a recently discovered inflammation pathway may play ...
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RUTH trial: Raloxifene linked to increased risk of venous thromboembolism and fatal stroke

The RUTH ( Raloxifene Use for The Heart ) trial is a randomized, placebo-controlled, double-blind trial designed to determine whether ...
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Scyllo-inositol appears promising for Alzheimer's disease

Canadian researchers found that certain variants of a simple sugar ameliorate Alzheimer's-like disease in mice. The new studies show that ...
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More than one-third of disaster victims may suffer from stress disorder

In the year after a terrorist attack, tornado hurricane or other natural or man-made disaster, 30 to 40 percent of ...
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Brain metastases: WBRT added to focused radiotherapy may reduce the likelihood of recurrences

A study, published in the JAMA, found that adding whole-brain radiation therapy to highly-focused radiation therapy does not improve ...
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Spirometry underused in patients with COPD

At least two thirds of patients with chronic obstructive pulmonary disease ( COPD ) do not receive lung function testing ...
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Community acquired pneumonia: effectiveness of discontinuing antibiotic treatment after 3 days versus 8 days

A study found that taking antibiotics for three days is just as effective for community acquired pneumonia as continuing treatment ...
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Imatinib attacks prostate cancer in mouse model by destroying its blood supply

Researchers from The University of Texas M. D. Anderson Cancer Center reported in the Journal of the National Cancer Institute ...
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Green tea: antioxidant protective effects of the polyphenolic EGCG

There is a lower incidence of cardiovascular disease and cancer in Asia where people smoke heavily, which may be accounted ...
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Increased sensitivity to nerve signals might offer a new approach to diabetes

Nerve signals relayed directly to the pancreas after eating a meal play a critical role in normal blood glucose control. Therefore, ...
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Sibutramine linked to QT interval prolongation

Sibutramine ( Meridia/Reductil ) is a serotonin and norepinephrine re-uptake inhibitor, approved for the management of obesity and overweight. In ...
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Antidepressants don’t seem to be related to suicide attempts and death in adults

Antidepressants may be associated with suicide attempts and death in severely depressed children and adolescents but not in adults. The ...
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Acupuncture on stroke rehabilitation: no clear evidence

Stroke is the third leading cause of death in Western society. It is also a main cause of adult disability ...
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Incidence of hypertension reduced with early intervention

A study involving researchers at University of Texas Southwestern Medical Center has concluded that treating pre-hypertension with medication and lifestyle ...
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Alzheimer's disease: THC inhibits the enzyme acetylcholinesterase

Researchers at The Scripps Research Institute have found that the active ingredient in marijuana, tetrahydrocannabinol or THC, inhibits the formation ...
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Salmeterol can worsen asthma symptoms

Asthma experts at the University of Iowa have added their voices to growing concerns about the risk associated with Salmeterol, ...
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Experts: concerns over the asthma drugs Salmeterol and Formoterol

Experts have raised concerns over the drugs Salmeterol and Formoterol, calling on the EMEA ( European Agency for the Evaluation ...
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Ankylosing spondylitis: Humira approved for reducing signs and symptoms

The FDA ( Food and Drug Administration ) has approved Humira ( Adalimumab ) for reducing signs and symptoms in ...
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FDA has approved new use for Plavix: STEMI myocardial infarction

The FDA ( Food and Drug Administration ) has approved the use of Plavix ( Clopidogrel ) for treatment of ...
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Epilepsy: Valproate linked to high risk for fetal death and birth defects

A study, published in the journal Neurology, found that the epilepsy drug Valproate ( Depacon/Depakene/Depakote ) is associated with higher ...
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Potential benefits and risks of treatment with antidepressants during pregnancy

The FDA ( Food and Drug Administration ) announced important new information from two recent studies that should be considered ...
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Combined use of triptans and antidepressants may result in life-threatening serotonin syndrome

The FDA ( Food and Drug Administration ) announced important new information on possible risks associated with the combined use ...
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Preoperative statin therapy linked to reduced cardiac mortality after CABG

Statin therapy in ambulatory populations is associated with a significant reduction in adverse cardiovascular events, including death and myocardial infarction. ...
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Bacteria: H-NS protein recognizes foreign DNA and prevents it from becoming active

A study, led by University of Washington, showed that bacteria like Salmonella have a complicated immune system that helps them ...
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Elk-1, a transcription factor, may play a role in cell death and mitochondria-related diseases

Researchers at the University of Pennsylvania School of Medicine discovered that a protein called Elk-1 interacts with mitochondria, suggesting that ...
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First trimester of pregnancy: ACE inhibitors linked to increased risk of birth defects

A study, led by William Cooper, at the Monroe Carell Jr. Children's Hospital at Vanderbilt University Medical Center, found infants ...
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Adolescents with negative body image concerns are more likely to be depressed, anxious, and suicidal

A study by researchers at Bradley Hospital, Butler Hospital and Brown Medical School, found that adolescents with negative body image ...
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Some patients with cardiogenic shock survive years after aggressive treatment

Despite advances in treatment, people with a myocardial infarction who survive the first hit and get to a hospital remain ...
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Acomplia may be dangerous for women of reproductive age

Anandamide is a lipid signal molecule that was the first endogenous agonist for cannabinoid receptors to be discovered. Cannabinoid receptor ...
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Quetiapine as effective as Risperidone for treatment of schizophrenia

The QUARTZ ( Quetiapine Fumarate and Risperidone in the Treatment of Patients with Schizophrenia ) trial found that Quetiapine ( ...
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Sutent is a promising agent for treatment of metastatic renal cell cancer

A study suggests that Sunitinib ( Sutent ) is a promising agent for treatment of metastatic renal cell cancer, currently ...
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Breast cancer: Raloxifene and Tamoxifen are both effective but have different side effects

Two studies found that Raloxifene ( Evista ) and Tamoxifen ( Novaldex ) are both effective in reducing the risk ...
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Lung cancer: ICAM, a new predictor for treatment response and survival

Researchers at the Ireland Cancer Center of University Hospitals of Cleveland have found a promising, novel biomarker that may be ...
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Vitamin D and Calcium supplements have varied effects on breast cancer risk

A large clinical trial reported that supplementation with Calcium and Vitamin D did not reduce breast cancer risk in the ...
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Sunitinib shows promise in children with metastatic gastrointenstinal stromal tumor resistant to Imatinib

A small pilot study from researchers at Dana-Farber Cancer Institute has shown that children with a rare digestive-tract cancer that ...
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Lung cancer: radiation therapy shown to increase survival

Treating certain lung cancer patients with surgery followed by radiation therapy can improve their chances of long-term survival, according to ...
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Mutation in gene for PDE11A associated with development of micronodular adrenocortical hyperplasia

Researchers at the National Institutes of Health ( NHI ) have discovered that a rare tumor of the adrenal glands ...
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Sexual desire and migraine headache may be linked

A study from researchers at the Wake Forest University School of Medicine suggests that not all headache sufferers avoid sexual ...
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A gene expression signature for Burkitt lymphoma identified

A study involving the University of Nebraska Medical Center ( UNMC ), the National Cancer Institute ( NCI ) ...
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Rimonabant, a new drug for weight loss

Rimonabant ( Acomplia ) is an oral selective cannabinoid CB1 receptor antagonist. It is licensed as an adjunct to diet ...
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Hedgehog signals linked to an increase in the density of blood vessels in the heart

The new concept for treating coronary artery disease is to induce hearts to grow their own new blood vessels to ...
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Esomeprazole more effective than Lansoprazole in maintaining healing of erosive esophagitis

A new study, involving more than 1,000 patients with healed erosive esophagitis, has shown that Esomeprazole ( Nexium ) is ...
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Sibutramine shouldn't be used in combination with SSRI antidepressants due to a possible risk of serotonin syndrome

Sibutramine ( Meridia/Reductil ) is a noradrenaline and serotonin reuptake inhibitor indicated for weight loss. It has been available in ...
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Non-small cell lung cancer: disease control rate may be a more powerful predictor of survival than tumor shrinkage

Researchers evaluate the effectiveness of a new antitumoral therapy by looking at how tumors respond to it. But in the ...
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Head and neck cancer: Docetaxel combined with standard chemotherapy reduces mortality by nearly 30 percent

Researchers from Dana-Farber Cancer Institute in Boston found that the addition of Docetaxel ( Taxotere ) to an initial chemotherapy ...
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Donepezil: no evidence to support the use for patients with mild cognitive impairment

Problems with memory which do not meet the diagnostic criteria for dementia, usually called mild cognitive impairment ( MCI ), ...
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Breathing exercises can cut inhaler use in mild asthma

A research, published in the journal Thorax, found that breathing techniques can cut the use of reliever inhalers by more ...
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The Cochrane Library: news alert, Issue 3 - 2006

This alert highlights some of the key health care conclusions and their implications for practice as published in The Cochrane ...
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Preterm or low birthweight infants at increased risk of hyperactivity disorder

A research, published in the Archives of Disease in Childhood, suggests preterm or low birthweight infants are up to three ...
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Lack of sleep linked to increased risk of hypertension

A study released by Columbia University's Mailman School of Public Health and the College of Physicians and Surgeons, found that ...
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Cancer cells may move via wave stimulation

Researchers at Mayo Clinic have uncovered a new cellular secret that may explain how certain cancers spread. If the mechanism that ...
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Insulin is critical for blood vessel formation

For people with type 2 diabetes, the death rate from a first myocardial infaction is two to three times the ...
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The Cochrane Library: news alert, Issue 2 - 2006

This alert highlights some of the key health care conclusions and their implications for practice as published in The Cochrane ...
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Parkinson's: single mutated copy of parkin may lead to earlier symptom onset

Mutations in a gene already known to play a role in causing an inherited form of Parkinson disease may also ...
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Prostate cancer: PSA density, a new predictor of disease for overweight men

Studies suggest that testing blood for prostate specific antigen ( PSA ) alone does not produce an ideal predictor of ...
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Gene therapy accelerates healing of damaged skeletal muscle

Researchers at the University of Pittsburgh School of Medicine have successfully used gene therapy to accelerate muscle regeneration in experimental ...
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Advanced kidney cancer: Sunitinib shows significant benefits over Interferon-alpha

Sunitinib ( Sutent ) is more effective than the current standard cytokine treatment given as an initial therapy for patients ...
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Breast-sparing surgery an option for women with breast cancer gene mutation

The women diagnosed with breast cancer who carry a certain genetic mutation can have breast-sparing surgery but should consider hormonal ...
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Preventive surgery reduces the risk of BRCA-associated breast and ovarian cancers

A multicenter study is the first to suggest that the prophylactic removal of the ovaries and fallopian tubes may provide ...
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Association between hematopoietic stem cells and osteoblasts may be important to stem cell function

Until now, researchers didn't know exactly where to find blood-forming stem cells – the only cells capable of forming all ...
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Coxsackievirus has evolved an indirect route of attack

A common virus that causes meningitis and heart inflammation takes a "back door" approach to evade natural barriers, then exploits ...
Leggi articolo

Ebola virus infection: antisense drugs protect non-human primates from lethal disease

Researchers have developed a successful strategy for interfering with Ebola virus infection that protected 75 percent of nonhuman primates exposed ...
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Many patients on diuretics have abnormal sodium and potassium levels

One in five patients taking diuretics commonly prescribed for high blood pressure or heart conditions end up with reduced sodium ...
Leggi articolo

Complex infection fighting mechanism described, new light on autoimmune disorders

Researchers at Yale School of Medicine reported in Nature Immunology how infection fighting mechanisms in the body can distinguish between ...
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Different factors predispose to chronic fatigue syndrome

Experts believe that chronic fatigue syndrome ( CFS ) is a complex disorder caused by many different factors. Chronic fatigue syndrome ...
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Obese adolescents: Sibutramine added to behavior therapy reduces BMI and body weight

Sibutramine ( Meridia/Reductil ) added to a behavior therapy program reduced BMI ( body mass index ) and body weight ...
Leggi articolo

Death in mammalian cells overloaded with saturated fat: role of EF1A-1 protein

Researchers at Washington University School of Medicine in St. Louis have identified a protein that triggers death in mammalian cells ...
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Age-related macular degeneration may be linked to quality of dietary carbohydrates

Age-related macular degeneration ( AMD ), one of the leading causes of vision loss in older adults and a person's ...
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Chronic myelogenous leukaemia: after five years on Gleevec overall survival reaches 89 percent

A study of the Oregon Health & Science University ( OHSU ) Cancer Institute has shown that the overall survival ...
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Dicer enzyme involved in RNA interference

A team of Howard Hughes Medical Institute ( HHMI ) researchers has peeled back some of the mystery of how ...
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CaR essential for localization of blood stem cells

Researchers at the Massachusetts General Hospital ( MGH ) Center for Regenerative Medicine and the Harvard Stem Cell Institute ( ...
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Tool to silence genes in specific tissues using RNAi developed

Reporting in the journal Genes and Development, investigators at The University of Texas M. D. Anderson Cancer Center have developed ...
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miRNA signature in solid tumors identified

Researchers have discovered that a wide variety of different cancers actually share something in common, a molecular "signature" made up ...
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Genetically engineered muscle-derived stem cells can repair cartilage

Damage to articular cartilage frequently occurs due to injury or illness, and can lead to degenerative disease. Treatments and experimental ...
Leggi articolo

Statins as potential modifiers of rheumatoid arthritis

A study found that statins have beneficial effect on rheumatoid arthritis cells in vitro. Statins, a class of drugs widely used ...
Leggi articolo

Avian flu transmission to humans may be higher than thought

A study suggests that there is an association between direct contact with dead or sick poultry and flu-like illness in ...
Leggi articolo

Depression: brain imaging can predict effectiveness of cognitive behavior therapy

Brain imaging can predict whether or not cognitive behavior therapy ( CBT ) will help a patient recover from depression, ...
Leggi articolo

12.5 kDa cystatin could be used to diagnose multiple sclerosis

Johns Hopkins researchers found that a protein found only in cerebrospinal fluid ( CSF ) that they say might be ...
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Statin use linked to reduced risk of nuclear cataract

The statins are associated with a lower incidence of nuclear cataract, the most common type of age-related cataract. Statins are widely ...
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NICE and British Hypertension Society: updated clinical guideline on the management of hypertension

The NICE ( National Institute for Health and Clinical Excellence ) and the National Collaborating Centre for Chronic Conditions, in ...
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Hepatotoxicity with black cohosh

Black cohosh ( Cimicifuga racemosa ) has a long history of traditional use in North American Indian medicine and has ...
Leggi articolo

Interactions with macrolide antibiotics

In 10 years from 1995 to 2004, ADRAC ( Adverse Drug Reactions Advisory Committee ) received 31 reports of a ...
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Nerve damage in complex regional pain syndrome-I discovered

Researchers at Massachusetts General Hospital ( MGH ) have found the first evidence of a physical abnormality underlying the chronic ...
Leggi articolo

Soy: no evidence that isoflavones stimulate cell growth in breast tissue

Research in monkeys suggests that the natural plant estrogens found in soy do not increase markers of breast cancer risk ...
Leggi articolo

Pregnancy: newer antidepressants linked to persistent pulmonary hypertension in newborns

The women who are taking antidepressants known as SSRI ( selective serotonin reuptake inhibitors ), and who are pregnant or ...
Leggi articolo

Caffeine limits blood flow to heart muscle during exercise

In healthy volunteers, the equivalent of two cups of coffee reduced the body's ability to boost blood flow to the ...
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Cryopyrin protein responds to invading bacteria by activating of IL-1beta

Researchers at the University of Michigan Medical School have discovered that a protein called cryopyrin responds to invading bacteria by ...
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