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A novel factor, BMP-6, stimulates cartilage growth from stem cells

Researchers at Duke University Medical Center and Pratt School of Engineering found that a novel growth factor significantly improves the ...
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Breast cancer: soy intake may be associated with reduced risk

A meta-analysis found that soy intake may be associated with a small reduction in the risk of breast cancer. However, because ...
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Mild cognitive impairment, the protective effect of education

Researchers at Mayo Clinic have found that mild cognitive impairment, a disorder considered a strong early predictor of Alzheimer's disease, ...
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Cardura increases risk of heart failure

A study, conducted at the San Francisco VA Medical Center, found that Cardura ( Doxazosin ), an alpha-adrenergic blocker commonly ...
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Fingolimod shows benefits in patients with relapsing multiple sclerosis

The Phase II trial data showed that Fingolimod ( FTY720 ) taken once-daily during the initial six months of treatment ...
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Ibuprofen interferes with antiplatelet activity of Aspirin

Ibuprofen can interfere with the anti-platelet effect of low dose Aspirin ( 81 mg per day ), potentially rendering Aspirin ...
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Multiple sclerosis: Campath more effective than Rebif

Two-year interim results from a Phase 2 trial comparing Campath ( Alemtuzumab ) with Rebif ( Interferon beta-1a ) for ...
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Risk of death linked to COX-2 inhibitors and nonselective NSAIDs after acute myocardial infarction

Myocardial infarction survivors taking COX-2-selective (NSAIDs) inhibitors or high dosages of nonselective nonsteroidal antiinflammatory drugs ( NSAIDs ) are at ...
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Colchicine toxicity with concomitant use of Clarithromycin

There have been post-marketing reports of Colchicine toxicity with concomitant use of Clarithromycin ( Biaxin/Klacid ) and Colchicine, especially in ...
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Intrahepatic cholestasis during pregnancy associated with other liver diseases later in life

A retrospective case-control study of 21,008 women in Finland has found that those with intrahepatic cholestasis of pregnancy ( ICP ...
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Non-alcoholic steatohepatitis: ascites is the most common complication of cirrhosis

Cirrhosis related to non-alcoholic steatohepatitis ( NASH ) is associated with fewer complications and a lower mortality compared to cirrhosis ...
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Epinephrine QT stress test reveals concealed type 1 long QT syndrome

Long QT syndrome is, sometimes fatal, heart rhythm disorder that is often present from birth.. It affects one in every ...
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Excess television may lead to overweight for preschoolers

In a study of more than one thousand preschool-age children, those who were exposed to more than two hours of ...
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Ginkgo biloba extract inhibits growth of breast tumor in mouse model

In the journal Anticancer Research, investigators reported that treating mice with an extract of leaves of Ginkgo biloba both before ...
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Relationship between oral and cardiovascular health

New research is reinforcing the longstanding belief that a connection exists between periodontal disease, or severe gum inflammation, and cardiovascular ...
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Taste gene may play role in smoking

Research on the genetics of smoking has focused on genes that are thought to be related to nicotine metabolism, personality ...
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Viagra might help in the Crohn's disease

Researchers found evidence that suggests Crohn's disease is caused by a weak immune response. The study, published in The Lancet, also ...
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Symptoms of anxiety and depression in childhood may encourage ecstasy use

A study found that children with symptoms of anxiety and depression may have an increased tendency to use ecstasy in ...
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Amytrophic lateral sclerosis: three proteins that may be first tools for confirming diagnosis, identified

Researchers from Mount Sinai School of Medicine have identified three proteins that are found in significantly lower concentration in the ...
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Antibody-interleukin complexes stimulate immune responses

Selective T cell stimulation could help improve treatment of autoimmune diseases such as rheumatoid arthritis, multiple sclerosis, or juvenile diabetes. ...
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Efficacy of Glucosamine, Chondroitin sulfate in patients with moderate to severe osteoarthritis knee pain

The dietary supplements Glucosamine and Chondroitin sulfate proved no better than a placebo in relieving osteoarthritis knee pain in most ...
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Statins improve erectile dysfunction of some men

Results of a small study showed promise in improving erectile dysfunction in men who had shown minimal reaction to Sildenafil ...
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Calcium supplements can reduce complications during pregnancy

Preeclampsia, the development of high blood pressure and protein in the urine during pregnancy and its more severe complications such ...
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Osteoporosis: Forteo not cost-effective compared with Fosamax

Researchers at the Stanford University School of Medicine have found that a new osteoporosis drug, called Teriparatide ( Forteo ), ...
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Huntington's disease: gene therapy preserves motor function in mouse model

Researchers at Rush University Medical Center, Chicago, and Ceregene, San Diego, have successfully used gene therapy to preserve motor function ...
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Folate supplementation reduces progression of leucoplakia

Folic acid supplements may prevent cancer progression and promote regression of disease. A small study found that 31 of 43 patients ...
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Immune response protects against brain tumor development

Researchers at The University of Texas M. D. Anderson Cancer Center have found that allergies and asthma that stimulate inflammation ...
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Familial factors in the development of lung cancer

Researchers at The University of Texas M. D. Anderson Cancer Center have documented a 25 percent increased risk of developing ...
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Anticancer response: multistep process in which proteins interact with NKG2D on NK cells identified

Researchers at Mayo Clinic have identified and characterized an important signal used by the human immune system to help destroy ...
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Breast cancer: two genes, HOXB13 and IL17BR, predict outcome

Researchers at Mayo Clinic reported that the expression of two novel genes within the tumors of women with early stage ...
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Antidepressant drugs linked to increased risk of death for heart patients

Researchers at Duke University Medical Center have found that patients with coronary artery disease who take commonly used antidepressant drugs ...
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Glioma: marrow-derived stem cells deliver cytokine interleukin-23 to kill tumor cells

Attaching a cytokine to neural stem cells derived from bone marrow, researchers at Cedars-Sinai Medical Center have developed a tool ...
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Activation of microRNA inhibits cancer gene in human cancer cells

Researchers have reported that tumor cells display a dramatic reduction of cancer-causing genes when a newly discovered method is used ...
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Type 2 diabetes: thiazolidinediones alter levels of Necdin and E2F4

Thiazolidinediones, or glitazones, are drugs commonly prescribed to patients with type 2 diabetes. Current FDA ( Food and Drug Administration )-approved ...
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Stent-grafting technique improves outcomes of carotid aneurysm repair

For patients with life-threatening aneurysms of the carotid artery in the neck, a minimally invasive stent-grafting technique can be just ...
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Exposure to fine particle air pollution linked to risk of respiratory and cardiovascular diseases

Being exposed to fine particle matter air pollution increases the risk for hospital admission for cardiovascular and respiratory diseases. Numerous studies ...
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Coffee consumption linked to increased risk of myocardial infarction for persons with CYP1A2 gene variation

Individuals who have a genetic variation associated with slower caffeine metabolism appear to have an increased risk of non-fatal myocardial ...
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Melatonin most effective for sleep when taken for off-hour sleeping

Researchers at Brigham and Women's Hospital and Harvard Medical School have found in a double-blind placebo-controlled clinical study, that Melatonin, ...
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Stem cell expansion with HOXB4

Transplantation of hematopoietic stem cells ( HSCs ) can save patients whose own hematopoietic system is defective or has been ...
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Dramatic rise in antibiotic-resistant community-acquired staph infections

Staph infections resistant to antibiotics, previously only associated with hospitalization or prior contact with the healthcare system, are now widespread ...
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Antidepressants may be associated with modestly increased risk of suicidality in children

An analysis of data from 24 clinical trials suggests that antidepressant medications may be linked to a modest increase in ...
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Depression, anxiety in girls linked to higher body mass index in women

Depression and anxiety disorders during childhood may be associated with a higher body mass index ( BMI ) into adulthood ...
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Genetic factors, neuroticism may be associated with future development of anorexia

In a large study of Swedish twins, anorexia nervosa appears to be moderately heritable and linked to neurotic behavior early ...
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Depressed older adults are more likely to become cognitively impaired

A study, conducted by researchers at the San Francisco VA Medical Center ( SFVAMC ) and the University of California ...
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Excess Folate linked to increased birth of twins after in-vitro fertilisation

The fortification with Folic acid might increase the rate of twin births after in-vitro fertilisation ( IVF ). In-vitro fertilisation is ...
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Epstein-Barr virus may increase risk of multiple sclerosis

Researchers have found that patients with multiple sclerosis carry a population of immune cells that overreact to Epstein-Barr virus. The virus, ...
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Sertraline may prevent recurring depression in diabetics

The antidepressant Sertraline ( Zoloft ) may reduce the risk of recurrent depression and increase the period of time between ...
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Liver transplants can be successful in HIV patients with hepatitis B

A study on HIV patients who also had hepatitis B virus ( HBV ) found that better outcomes are possible ...
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Type 1 diabetes: no improvement in heart disease rates over past 30 years

Researchers at the University of Pittsburgh Graduate School of Public Health ( GSPH ) discovered that while cases of premature ...
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New technique offers relief for patients with spinal tumors

A radiologist at the University of California - San Diego ( UCSD ) School of Medicine has developed a new ...
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Chronic hepatitis in pediatric liver transplant patients

A study on the long-term outcome of children undergoing liver transplants found that chronic hepatitis was common and that it ...
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Safety alerts in EMRs reduce rates of potentially dangerous drug interactions

The results of the Safety in Prescribing study, conducted by Kaiser Permanente’s Center for Health Research, showed that electronic medication ...
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Congestive heart failure: diuretics may not be best way to reduce water retention

Arginine vasopressin has been implicated in the renal water retention and dilutional hyponatremia associated with congestive heart failure. A study examined ...
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Malignant glioma: engineered adenovirus induces cells to die by autophagy

Researchers at The University of Texas M. D. Anderson Cancer Center reported in the Journal of the National Cancer Institute ...
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Efficacy and safety of Sunitinib in previously treated, advanced non-small cell lung cancer

A phase II study is assessing the safety and efficacy of Sunitinib ( Sutent ) in patients with advanced ...
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Advanced renal cell carcinoma: efficacy of Lapatinib in patients with high EGFR expression

A phase III clinical trial has shown that Lapatinib ( Tykerb ) slows cancer growth and improves survival in a ...
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Chronic myeloid leukemia: Dasatinib circumvents Imatinib resistance

Dasatinib ( Sprycel ) reverses the signs and symptoms of patients whose chronic myeloid leukemia has failed to respond to ...
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Esomeprazole reduces gastric ulcers in at-risk patients taking long-term NSAIDs

Two clinical trials found that Esomeprazole ( Nexium ) can reduce the incidence of gastric ulcers in patients at risk ...
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Varenicline can be an effective therapy for smoking cessation

Varenicline ( Chantix ) has shown effectiveness in helping smokers quit and abstain from smoking when compared to placebo and ...
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Coronary heart disease: transcendental meditation may improve cardiac risk factors

Transcendental meditation, a relaxation technique may decrease blood pressure and reduce insulin resistance among patients with coronary heart disease. Transcendental meditation, ...
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Fungal keratitis among soft contact lens wearers

Fusarium is associated with an increasing number of cases of keratitis. Infections caused by fungi can be devastating to both the ...
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Parkin mutations may influence age at onset of Parkinson's disease

The number of mutations in parkin gene, previously found to be associated with early-onset Parkinson's disease, may influence the age ...
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Erectile dysfunction: Viagra, Cialis and Levitra may be associated with visual loss

Eric Wooltorton has published in the Canadian Medical Association Journal ( CMAJ ) a review of visual loss associated with ...
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Hyponatremia associated with SSRI antidepressants in older adults

Researchers from University of the Sciences in Philadelphia have performed a review of the incidence, risk factors, mechanism, times of ...
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Paroxetine may cause adverse outcomes in neonates when used during pregnancy

Selective serotonin-reuptake inhibitors ( SSRIs ) are associated with neonatal withdrawal symptoms such as respiratory distress, irritability, lethargy, and tremors. In ...
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Cardiovascular risk factors are largely undertreated and undercontrolled in many regions of the world

A large scale global study on cardiac care has revealed that there is a gap between what is recommended and ...
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Routine ECGs for newborns would identify long QT syndrome

Italian heart specialists recommend to introduce ECG screening for all infants at around three to four weeks of age to ...
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Benefits of Candesartan added to ACE inhibitor in inhibition of progression of nephropathy

A study assessed if adding Candesartan ( Atacand ) to ACE ( angiotensin-converting enzyme ) inhibitors would delay progression of ...
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Advanced breast cancer: Herceptin cardiotoxicity is often reversible

A study in women with advanced breast cancer has found that cardiotoxicity associated with Trastuzumab ( Herceptin ) is reversible ...
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Abnormal glucose metabolism may contribute to chronic idiopathic axonal polyneuropathy

Abnormal glucose metabolism, which occurs when the body has difficulty processing glucose into energy, is twice as common among patients ...
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Implantable defibrillators may increase heart failure risk

Implantable cardioverter defibrillators ( ICDs ) reduce the risk of sudden cardiac death but may increase the risk of subsequent ...
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Stopping antiplatelet drug within 30 days of receiving a drug-eluting stent raises risk of death

Patients with myocardial infarction who stopped taking antiplatelet drugs within 30 days of receiving a drug-coated stent had nine times ...
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Diabetes: Genepin reverses some pancreatic dysfunctions

A Gardenia fruit extract traditionally used in Chinese medicine to treat the symptoms of type 2 diabetes does indeed contain ...
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Coffee drinking linked to lower risk for alcohol-related liver disease

Drinking coffee may be related to a reduced risk of developing the liver disease alcoholic cirrhosis. Cirrhosis progressively destroys healthy liver ...
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Poor persistence with osteoporosis medications increases fracture risk

Independent studies of patients in Belgium, Canada, and Germany confirm that there is a major gap in treating patients with ...
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Fenretinide reduces the risk of second breast cancers in young women

An Italian research team found that Fenretinide, a drug related to vitamin A, significantly cuts the risk of a second ...
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Rheumatoid arthritis does not increase risk of hearing loss

Researchers at Mayo Clinic have found that people with rheumatoid arthritis are no more likely to have hearing loss than ...
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D-Cycloserine can boost benefits of therapy for social anxiety disorder

Researchers from the Center for Anxiety and Related Disorders at Boston University have found that adding D-Cycloserine ( DCS ), ...
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Drug-induced hepatotoxicity: Acetaminophen, Ketek

Adverse drug reactions in the liver are the most common reason for drugs to be taken off the market. In an ...
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Cocaine linked to intracerebral hemorrhage in young adults

A fifth of young adults whose blood vessels ruptured inside their brain abused drugs and more than 40 percent had ...
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Periconceptional multivitamin use reduces the risk of preeclampsia

A study by researchers at the University of Pittsburgh found that women who are considering becoming pregnant may significantly reduce ...
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Regular use of COX-2 inhibitors associated with increased risk for non-Hodgkin lymphoma

Researchers at the University of California School of Medicine, San Francisco, have examined the association between long-term use of nonsteroidal ...
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Nonalcoholic fatty liver disease linked to increased risk of heart disease

A study on the relationship between nonalcoholic fatty liver disease ( NAFLD ) and heart disease found that patients with ...
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Onset of psychosis may be delayed by Olanzapine

A study, published in The American Journal of Psychiatry, has shown that for young people who clearly seem to be ...
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Inflammation markers identify fatigue in breast cancer survivors

Researchers at the University of California - Los Angeles ( UCLA ) have defined conditions associated with disabling fatigue that ...
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Melatonin improves mood in winter depression

Researchers at Oregon Health & Science University ( OHSU ) have found that Melatonin, a naturally occurring brain substance, can ...
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Exubera: no evidence available of an additional therapeutic benefit

IQWiG, The German Institute for Quality and Efficiency in Health Care, has published a comparative review of inhaled Insulin ( ...
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Low estrogen levels in men linked to increased risk for hip fracture

A study has found that men with low estrogen levels have an increased risk for future hip fracture, and those ...
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Vioxx: myocardial infarction can occur within the first two weeks of use

A study by investigators at the McGill University Health Centre ( MUHC ) found that a quarter of patients ...
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All men with erectile dysfunction should be monitored for heart and vascular disease

An Italian study of men with erectile dysfunction ( ED ) and coronary artery disease ( CAD ) has shown ...
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Progeria, a model to explore cardiovascular disease

In children with progeria, a mutant protein accumulates in blood vessel cells, hampering their ability to grow and multiply or ...
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No significant association between levels of physical activity and colon cancer incidence in women

A prospective cohort study of 31,783 American women has found no significant association between levels of physical activity and colon ...
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Brain cells that produce dopamine depend upon a sex-specific gene

Researchers at University of California – Los Angeles ( UCLA ) have discovered that a sex gene, responsible for making ...
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Corticosteroids associated with poor outcomes, death in the trauma intensive care unit

Patients in the trauma intensive care unit who receive corticosteroids may have more infections, longer stays in intensive care or ...
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Stressed-out women more likely to miscarry early

A study of a small population of women found that women who exhibit signs of stress are three times more ...
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Gum-chewing may speed recovery after colon surgery

A small study suggests that chewing gum after colon surgery may speed the return of normal bowel function and shorten ...
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Statins, beta-blockers lessen myocardial infarction risk

A research from the Stanford University School of Medicine suggests that statins and beta-blockers can steer patients away from having ...
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TNF level predicts who will develop deadly complication after bone marrow transplant

Researchers could determine one week after a bone marrow transplant which patients were likely to develop a serious and deadly ...
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Intracerebral hemorrhage: lower doses of tPA safer

A Johns Hopkins study has shown that patients treated for intracerebral hemorrhage, survived more often if given 1 milligram instead ...
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Anabolic steroids increase myocardial infarction risk and cause liver damage

A study that measured the effects of anabolic steroids on men with HIV wasting disease found that anabolic steroids cause ...
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