Brain structures contribute to asthma

A study by University of Wisconsin-Madison researchers and collaborators, published in the Proceedings of the National Academy of Sciences ( ...

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Farnesyltransferase inhibitors show promise for treating progeria

A research team led by the National Human Genome Research Institute ( NHGRI ), part of the National Institutes of ...

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An analog of Celecoxib seems to halt tumor growth

An interdisciplinary team of researchers, led by Axel H. Schšnthal, at the Keck School of Medicine of USC ( University ...

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Benzodiazepines effective against alcohol withdrawal seizures

A review of recent studies has found that tranquilizers work better than placebo at treating the symptoms of alcohol withdrawal ...

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Bone marrow transplantation, some children have dental abnormalities that favor severe bacterial infections

Many children who undergo bone marrow transplantation ( BMT ) as part of cancer treatment already have dental abnormalities that ...

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Stable coronary artery disease, FDA approves Aceon to reduce risk of cardiovascular mortality or non-fatal myocardial infarction

FDA ( Food and Drug Administration ) has approved Aceon ( Perindopril erbumine ) tablets for the treatment of patients ...

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iPLEDGE, a risk management program to enhance safe use of Isotretinoin for treating severe acne

FDA ( Food and Drug Administration ) has approved a program for Isotretinoin (Accutane and its generics), called iPLEDGE, aimed ...

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FDA clears Invader UGT1A1 Molecular Assay, a pharmacogenetic test

FDA ( Food and Drug Administration ) has cleared Invader UGT1A1 Molecular Assay for in vitro diagnostic use. It is the ...

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Cognitive therapy reduces repeat suicide sttempts by 50 percent

A study, performed at University of Pennsylvania, found that recent suicide attempters treated with cognitive therapy were 50 percent less ...

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Acetaldehyde’s role in the carcinogenicity of alcohol beverage consumption

Drinking alcoholic beverages has been linked to an increased risk of upper gastrointestinal cancer and other types of cancer. Researchers looking ...

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Misoprostol offers alternative to surgical treatment after miscarriage

A study by researchers, at the National Institute of Child Health and Human Development of the National Institutes of Health ...

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Methamphetamine abuse and HIV infection cause changes in brain structure

A research published in the American Journal of Psychiatry indicates that methamphetamine abuse and HIV infection cause significant alterations in ...

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Orexin plays a key role in food and drug-seeking behavior

A research performed in rats suggests that orexin, a brain chemical involved in feeding behavior, arousal, and sleep, also plays ...

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Visceral pain, Oxycodone seems to be more effective than Morphine

A study in healthy volunteers suggests that the use of Oxycodone ( OxyContin ), a synthetic opioid compound, may be ...

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Ways to avoid hazards of heart bypass under study

The heart-lung bypass machine that stills the heart while surgeons bypass clogged arteries or repair a cardiac malformation can also ...

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Plague, a family of virulence factors identified

Researchers at Duke University Medical Center have identified a family of virulence factors that make the bacterium responsible for the ...

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Malaria, PfRh4 gene allows Plasmodium falciparum to switch to an alternative mode of blood cell invasion

The malaria parasite Plasmodium falciparum uses different pathways to invade red blood cells, evading the body's immune system and complicating ...

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Malaria, Artesumate better than Quinine in reducing the risk of death

A trial in malaria patients from four countries has shown a clear benefit of a drug derived from an ancient ...

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Cancer vaccines: particular ligands turn off the suppressive function of Treg cells

Researchers at Baylor College of Medicine ( BCM ) at Houston showed that special stretch of genetic material may turn ...

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Two specific gene variants linked to stroke after heart surgery

Researchers at the Duke University Medical Center have discovered that patients who have two specific gene variants are more than ...

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Long-term use of Aspirin reduces risk of colorectal cancer

Randomized trials of short-term Aspirin use for prevention of recurrent colorectal adenoma have provided compelling evidence of a relationship between ...

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Fulminant hepatic failure, high blood lactate levels may indicate poor prognosis

A study on fulminant hepatic failure ( FHF ) examined whether patients would benefit from a transplant. The results, published ...

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FDA approves Singulair for perennial allergic rhinitis

Fda ( Food and Drug Administration ) has approved Singulair ( Montelukast ) for the relief of symptoms of perennial ...

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Chronic hepatitis B, Telbivudine achieves primary endpoint in GLOBE trial

The phase III GLOBE trial for Telbivudine successfully reached its primary, composite efficacy endpoint of therapeutic response at one ...

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Belatacept protects kidneys after transplant

Belatacept ( LEA29Y ), a new drug that selectively blocks immune responses, has proved as effective in preventing acute kidney ...

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First-trimester risk assessment for trisomy 21

In a study undertaken by investigators at the Harris Birthright Research Centre for Fetal Medicine, King's College Hospital, London and ...

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Transmission of hepatitis C among family members

A study assessed the incidence and risk factors associated with hepatitis C infection in rural Egypt. The prevalence of antibodies to ...

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Parkinson's, microtubules are a critical target of environmental toxins

Researchers from the University at Buffalo have described for the first time how rotenone, an environmental toxin linked specifically to ...

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Nanophthalmos caused by an alteration in a gene called MFRP

Johns Hopkins researchers at the Wilmer Eye Institute have discovered the first human gene mutation that causes extreme hyperopia. The researchers ...

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CHr, a better screening test for infant iron deficiency

A study, published in the JAMA, demonstrated that unique blood test detects iron deficiency in infants earlier and more accurately ...

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The role of RNA in human immune response

Researchers at the University of Pennsylvania School of Medicine tested the role of RNA chemical modifications on immunity. They have demonstrated ...

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Endorphins play a role in the placebo effect

The University of Michigan study provides the first direct evidence that the brain's own pain-fighting chemicals, called endorphins, play a ...

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Lung cancer, diagnostic strategy, EUS-FNA, may help determine stage more accurately

Up to 40 percent of thoracotomies ( surgical incision of the chest wall often involving surgery of the lung ) ...

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Risky behaviors, gambling monkeys give insight into neural circuitry

Researchers at the Duke University Medical Center have pinpointed circuitry in the brains of monkeys that assesses the level of ...

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Hemophilia, gene therapy produces partial correction to bleeding problems in mouse models

A virus that typically infects insects could help with the development of gene therapy treatment for Hemophilia A. Researchers at the ...

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Database studies may not accurately estimate risk of myocardial infarction in Naproxen, Ibuprofen users

It is known that Aspirin, a non-selective, non-steroidal anti-inflammatory drug ( NSAID ) that inhibits cyclooxygenase ( COX ), reduces ...

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Rett syndrome, mouse model displays reduced cortical activity

A study demonstrated that spontaneous neuronal activity is reduced in the cortex of a knockout mouse model for the childhood ...

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Ovarian cancer: PKCi, a potential oncogene, could be used as a powerful predictive test

Researchers at The University of Texas M. D. Anderson Cancer Center have discovered a potential oncogene in ovarian cancer, which ...

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Prophylactic subcutaneous mastectomy reduces risk of developing breast cancer in women with BRCA1 and BRCA2 mutations

A study, published in Lancet Oncology, has demonstrated that prophylactic mastectomy reduces the breast cancer risk by 89.5 to 100 ...

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A new technique for creating human embryonic stem cells developed

Researchers have developed a new technique for creating human embryonic stem cells by fusing adult somatic cells with embryonic stem ...

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Mantle cell lymphoma, an experimental vaccine can prime the immune system

Researchers at The University of Texas M. D. Anderson Cancer Center and the National Cancer Institute have found that an ...

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Fanconi anemia, BRIP1 mutations may have a role in development of the disease

Researchers, led by scientists at Rockefeller University, found a gene mutation not previously known to be related to Fanconi anemia, ...

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Humira for the treatment of psoriatic arthritis and early rheumatoid arthritis, EU approves

European Commission approved Humira ( Adalimumab ) as a treatment for psoriatic arthritis and as first-line treatment of severe rheumatoid ...

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GRK2 enzyme, a potential biomarker for heart failure

Researchers at Jefferson Medical College have found an enzyme in the blood that could be a potential marker for heart ...

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Combination of surgery and radiation for spinal complications of cancer

A study, conducted by Roy Patchell and colleagues at the University of Kentucky and published in the Lancet, indicated the ...

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Medulloblastoma, young children at risk for impaired reading skills following irradiation

The results of the largest study of its kind, conducted by investigators at St. Jude Children's Research Hospital, Texas Children's ...

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One bacterial cell can stop the growth of another on contact

Researchers have discovered a new phenomenon in which one bacterial cell can stop the growth of another on physical contact. The ...

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Low risk of developing cancer after radiation exposure during virtual colonoscopy

A study, published in the journal Gastroenterology, showed that the risk of developing cancer as a result of being exposed ...

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Cancer of the esophagus may benefit from laparoscopic esophagectomy

Surgeons at the Oregon Health & Science University Digestive Health Center have developed a new technique that makes feasible and ...

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Enhancing innate immunity improves Crohn's disease symptoms

Most treatments for Crohn's, an autoimmune disorder, are geared to suppress the immune response, but a new study demonstrates that ...

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MicroRNAs play role in regulating oogenesis

Researchers at Northwestern University and Carnegie Mellon University have found that a recently described class of molecules called microRNAs ( ...

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Low levels of folic acid linked to low birth weight

A study found that mothers-to-be with lower levels of the vitamin folate in their body during early pregnancy are more ...

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Mifepristone linked to rare cases of fatal bacterial infections

The abortion drug Mifepristone ( Mifeprex, RU-486 ) has been linked to rare cases of fatal bacterial infections, but until ...

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Bone marrow may be source of new egg-cell generation in adult mammals

Last year researchers at the Massachusetts General Hospital ( MGH ) announced surprising findings that female mice retained the ability ...

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Diabetics have higher rates of complications after ankle fracture surgery

Duke University Medical Center researchers have found that patients with diabetes who require surgery for ankle fractures have significantly higher ...

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Waist size is associated with the metabolic syndrome in children

A study found that waist circumference is associated with insulin resistance in children and may offer a simple way to ...

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Media exposure influences use supplements to improve physique among teens

A nationwide survey of more than 10,000 adolescents, published in the journal Pediatrics, reports a high rate of concern about ...

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Brightly-coloured fruit and veg may protect against arthritis

Researchers at the University of Manchester's Medical School have discovered that eating more brightly-coloured fruits and vegetables like oranges, carrots ...

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Damage to the inner ear caused by antibodies to IESCA can destroy hearing

In thousands of people each year, the immune system attacks the inner ear, home to the tiny, delicate structures that ...

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MRI-MNP technique allows to detect pancreatic inflammation in type 1 diabetes

An obstacle to early detection of type 1 diabetes has been the lack of direct, non-invasive technologies to visualize inflammation ...

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Cranberry juice modulates atherosclerotic vascular dysfunction

Cranberries over the years have been identified with preventing or ameliorating urinary tract infections and playing a positive role gum ...

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PCSK9 protein, a new target for cholesterol-lowering drugs

Mice lacking a key protein involved in cholesterol regulation have low-density lipoprotein ( LDL ) levels more than 50 percent ...

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Early warning signs of Alzheimer's show up across cognitive areas years before diagnosis

Swedish meta-analysis of 47 studies finds clear patterns across thousands of people who went on to be diagnosed with Alzheimer's ...

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Anti-inflammatory activity of Alzheimer's disease drugs discovered

The mechanism of anti-Alzheimer's disease drugs that inhibits the production of a destructive, inflammation-causing protein in the brain has been ...

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Amygdala plays pivotal role during an emotional experience

Researchers led by UC Irvine neuroscientists has identified how the brain processes and stores emotional experiences as long-term memories. The research, ...

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Ovarian cancer, km23 protein may be early warning

Researchers at Penn State College of Medicine found a signal that could lead to earlier detection and treatment of ovarian ...

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A tool for decoding gene functions in mammals developed

A project between American and Chinese researchers developed a way to study the function of genes in mice and man ...

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Family environment is a significant predictor of adolescent obesity

A study examined the factors that contribute toward children becoming overweight or obese in early adulthood. Parents have a strong influence ...

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A link between vascular gene and Alzheimer's disease discovered

Researchers at the University of Rochester Medical Center have discovered a link between a prominent developmental gene and neurovascular dysfunction ...

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Astrocytes appear to play a key role in the development of epilepsy

A study, published in Nature Medicine found that star-shaped brain cells that are often overlooked by doctors and researchers ...

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Prostate cancer, activated Stat5 protein can predict outcome

Researchers from Lombardi Comprehensive Cancer Center at Georgetown University found that testing for an activated Stat5 protein in prostate tumor ...

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Cell surface enzyme matriptase can cause cancer

Researchers at the National Institute of Dental and Craniofacial Research ( NIDCR ) and colleagues found in animal studies that ...

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Possible mitochondrial damage with chronic use of Nitroglycerin for chest pain

A study by Howard Hughes Medical Institute investigators at Duke University Medical Center has provided evidence on how Nitroglycerin relieves ...

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First ever gene therapy success for congenital muscular dystrophy achieved

Researchers at the University of Pittsburgh reported the first study to achieve success with gene therapy for the treatment of ...

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Educational and nutritional intervention improves the well-being of breast cancer survivors

A study by researchers at Carnegie Mellon University, the University of Pittsburgh Medical Center and Emory University showed that women ...

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Humira plus Methotrexate effective for long standing rheumatoid arthritis

Combined treatment with Adalimumab ( Humira ) and Methotrexate is about five times more effective than Methotrexate alone in people ...

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Anxiety disorders can compromise success of alcohol-dependence treatment

Researchers at the University of Minnesota found that individuals who have an anxiety disorder when starting treatment for alcohol dependence ...

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Decreased energy production in insulin-resistant offspring of type 2 diabetic parents

A decline in energy production by mitochondria seems to be a key problem leading to insulin resistance, and thus to ...

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Angioplasty, more experienced doctors linked to better outcomes

In the most up-to-date analysis yet of this contentious issue, researchers from the University of Michigan Cardiovascular Center and the ...

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Variants of the protein SH2-B might underlie obesity

A weight control protein with a key role in the brain's ability to monitor body fat content may yield new ...

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Oral contraceptives, calcium in diet can reduce risk of osteoporosis

Purdue University research has showed that women who take oral contraceptives can counteract bone loss by making sure they have ...

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Anemia, new route to hemoglobin synthesis discovered

Researchers studying zebrafish that die from anemia have discovered a new pathway for the synthesis of heme, iron-containing molecule that ...

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Sirt1 protein allows to better control blood glucose levels in a murine model

Researchers at Washington University School of Medicine in St. Louis have found that a protein called Sirt1 enhances the secretion ...

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Heparin antibodies in hemodialysis patients associated with more adverse outcomes

Researchers at Mayo Clinic searching for explanations of high mortality rates among kidney failure patients undergoing hemodialysis are focusing their ...

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Diabesity, increasing glucose processing in the liver can lower blood glucose

Researchers at the University of Minnesota have shown that increasing the concentration of a key regulator involved in glucose metabolism ...

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Heart failure, anemia is a predictor of increased risk of death

Studies have shown that low hemoglobin, which may result in anemia, is more common among patients with heart failure than ...

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Analgesic drugs linked to high blood pressure in women

Women who consume higher doses of non-aspirin painkillers are much more likely to develop high blood pressure than women who ...

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Hospitalizations because of varicella down dramatically

CDC researchers assessed 1994-2002 trends in varicella-related hospitalizations, ambulatory visits, and associated expenditures using a national insurance data set. Since the ...

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Heart attack at off-hours and weekend linked to higher risk of death

A study showed that patients who arrive at a hospital during off-hours and on the weekend following a heart attack ...

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Guidelines for the prevention and management of postoperative atrial fibrillation

The American College of Chest Physicians ( ACCP ) released the first evidence-based clinical practice guidelines for the prevention and ...

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Role of O-GlcNAc in diabetes-related erectile dysfunction

Researchers have found that one particular simple sugar, present in increased levels in diabetics, interferes with the chain of events ...

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Loss of p63 gene accelerates aging in murine model

Researchers at Cold Spring Harbor Laboratory have discovered that the loss of a gene called p63 accelerates aging in mice. ...

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Breast cancer detected through mammography has better prognosis

Researchers at The University of Texas M. D. Anderson Cancer Center found that women whose breast cancer was detected by ...

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Laser-induced fluorescence spectroscopy for detecting inflammatory cells in blood vessels

In a study involving laboratory rabbits, a device that stimulates, collects and measures light emissions from body tissues has been ...

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Glioblastoma multiforme, combined gene therapy seems effective in a murine model

Glioblastoma multiforme ( GBM ) is the most common and deadly of brain cancers. Because GBM is so aggressive, the disease ...

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Neural stem cells linked to malignant astrocytoma

Researchers at University of Texas ( UT ) Southwestern Medical Center found that stem cells in a certain region of ...

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Breast cancer, a set of genes linked to spread to lungs identified

Researchers at Memorial Sloan-Kettering Cancer Center ( MSKCC ) have identified a set of genes in breast tumors that appear ...

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The family of SIR2 genes is involved in controlling lifespan

Mice, rats, worms, flies, and yeast all live longer on a low-calorie diet, which also seems to protect mammals against ...

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Broccoli may help prevent or slow the progress of bladder cancer

Researchers have isolated compounds from the vegetable broccoli that they believe may help prevent or slow the progress of bladder ...

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Older people with new-onset diabetes have high risk of pancreatic cancer

Researchers in Mayo Clinic Cancer Center found that new onset of hyperglycemic diabetes in adults age 50 or older may ...

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