Viral targeting technology applied to cancer treatment

Researchers at Mayo Clinic, working with colleagues in Germany, have discovered a way to fight cancer by using parts of ...

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Proton beam radiation therapy for melanoma affecting eyes

Researchers in the United Kingdom have demonstrated that patients suffering from cancer affecting their eye can usually avoid visual handicap, ...

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Neuroblastoma, DNA microarray technology rapidly detects genetic changes

Researchers have developed a customized gene chip to rapidly scan tumor samples for specific DNA changes that offer clues to ...

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Prostate cancer, tumor growth is stopped through cellular senescence

Prostate cancer is caused by changes in several tumor suppressor genes including PTEN and p53. Up to 70 percent of men ...

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Acute lymphoblastic leukaemia, blood stem cell transplant of benefit for children

Children with very high-risk acute lymphoblastic leukaemia ( ALL ) benefit if they receive a blood stem cell transplant from ...

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Risk of breast cancer with hormone replacement therapy

A study suggests risk of developing breast cancer while taking hormone replacement therapy may be lower than we think. Researchers, ...

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Breast cancer, switch to Anastrozole after two years of Tamoxifen is beneficial

A study, published in The Lancet, demonstrated that switching treatment to the drug Anastrozole ( Arimidex ) after two years ...

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Lung cancer: EMP-1, a biomarker for resistance to treatment with Gefitinib

Researchers at Cedars-Sinai Medical Center have identified a protein called EMP-1 that is present in the tumors of patients who ...

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DWI technique to monitor ultrasound uterine fibroid treatment

Researchers at Johns Hopkins Medical Institutions have used a magnetic resonance imaging ( MRI ) technique called diffusion-weighted MRI ( ...

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Cosmic radiation increases risk of nuclear cataract in airline pilots

Airline pilots have an increased risk of nuclear cataracts compared with non-pilots, and that risk is associated with cumulative exposure ...

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Hormone gastrin linked to risk of colon cancer

Researchers at the University of Texas Medical Branch at Galveston ( UTMB ) have linked the hormone gastrin to the ...

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Nonmelanoma skin cancer is increasing among young adults

A study found the incidence of nonmelanoma skin cancer increasing among men and women under the age of 40. The overall ...

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Childhood cancers strongly linked to air pollution in early life

Childhood cancers are strongly linked to pollution from engine exhausts. The postal addresses of 22,500 children who had died of cancer ...

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Multiple sclerosis, lesion type may predict response to plasma exchange

A study showed that only multiple sclerosis ( MS ) patients with evidence for antibody deposition or complement activation in ...

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Elevated insulin levels increase levels of inflammatory markers

Moderately elevated levels of insulin increase the levels of inflammatory markers and beta-amyloid in plasma and in cerebrospinal fluid, and ...

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Folates reduce risk of developing Alzheimer’s disease

Results from a long-term National Institute on Aging study of diet and brain aging showed that adults who eat the ...

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Bcl-xL, a protein, prevents tissue injury but increases tumor growth

A study, conducted at Washington University School of Medicine in St. Louis. found that a protein that protects the body ...

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Asthma, T lymphocytes responsible for the airway thickening

Researchers at McGill University Health Center ( MUHC ) discovered that our body's own defense mechanism causes some of the ...

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Prostate cancer, lifestyle and diet may stop or reverse progression

A study, published in Journal of Urology, found that men with early stage prostate cancer who make intensive changes in ...

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An enzyme, retinoid isomerase, linked to childhood blindness

Researchers at University of California – Los Angeles ( UCLA ) have discovered that RPE65, a gene missing in infants ...

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A new gene implicated in the cause of type 2 diabetes discovered

Investigators at Joslin Diabetes Center first identified genes that were altered in their level of expression in islets isolated from ...

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Ovarian cancer risk and high intake of milk products and lactose

An meta-analysis of 21 epidemiological studies found some support for the hypothesis that high intake of milk products and lactose ...

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Defective gene associated with two immune system disorders

Defects in a single gene can result in two immune system disorders that leave affected individuals vulnerable to frequent or ...

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Allergies: more than half the US population is sensitive to one or more allergens

A large study found that more than fifty percent of the U.S. population tested positive to one or more allergens. The ...

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Celebrex for the treatment of ankylosing spondylitis, approved by FDA

The FDA ( Food and Drug Administration ) has approved the selective COX-2 inhibitor Celebrex ( Celecoxib ) for ...

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Diovan to reduce cardiovascular death in heart attack survivors at high risk, approved by FDA

The FDA ( Food and Drug Administration ) approved Diovan ( Valsartan ), an ARB ( angiotensin receptor blocker ), ...

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Achilles' heel of the herpes virus

Researchers at the University of Michigan discovered a receptor that appears to function as one "lock" that herpes simplex virus ...

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FDA approves Rozerem for the treatment of insomnia

FDA ( Food and Drug Administration ) has approved the New Drug Application ( NDA ) for Rozerem ( ...

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Gender may play a role in Alzheimer’s disease

Researchers from the Rush Alzheimer's Disease Center found that plaques and tangles in the brain, the changes seen in people ...

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Statins may lower mortality in patients with diastolic heart failure

Cardiologists at Wake Forest University Baptist Medical Center demonstrated statin therapy may improve survival in patients with diastolic heart failure ...

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Adderall XR, as a once-daily treatment for adolescents aged 13 to 17 with ADHD

FDA ( Food and Drug Administration ) has approved Adderall XR ( mixed salts of a single-entity amphetamine product ) ...

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CDK5 inhibitors for the treatment of Alzheimer’s disease

Researchers discovered three molecules that appear to inhibit a key perpetrator of Alzheimer's disease. Each of the three molecules protects ...

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Bacterium Moraxella catarrhalis involved in COPD

A ubiquitous bacterial strain is thought to be involved in chronic obstructive pulmonary disease ( COPD ). The bacterium, Moraxella ...

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Bacterial infections after abortion pill

Mifeprex ( Mifepristone ) has been available in the U.S. for almost 5 years, and more than 460,000 women in ...

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Guidant: corrective action about certain pacemakers

Guidant announced it is voluntarily advising physicians about important safety information regarding certain devices. Guidant apprised FDA of this action, ...

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Predicting the outcome of drug-induced liver disease

Drug-induced liver disease ( DILD ), a potential complication seen with some medications, is usually not life-threatening, but may occasionally ...

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Mutations in NOTCH1 gene cause aortic valve disease

By studying five generations of a Dallas family, UT Southwestern Medical Center researchers have discovered that a mutation in a ...

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Menopausal hormone therapy, women report various symptoms after stopping hormones

A study, published in JAMA, found that over half of women who began menopausal hormone therapy because of symptoms such ...

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Concerns over Natrecor, a drug for acute decompensated CHF

Eric J. Topol, chair of the Department of Cardiovascular Medicine at the Cleveland Clinic, asks, How can a drug that ...

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FDA asks to withdraw Palladone for safety reasons

FDA ( Food and Drug Administration ) has asked Purdue Pharma L.P., the makers of Palladone, to withdraw it from ...

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Black cohosh: reports of liver toxicity

Black cohosh ( Cimicifuga racemosa ) is an herbal medicine used mainly to alleviate menopausal symptoms. Adverse reactions ( Ars ) ...

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Avandia: decreased HDL cholesterol levels

Avandia ( Rosiglitazone ) is a member of the thiazolidinedione family of oral hypoglycemic agents used to improve glycemic control ...

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Ibuprofen: Stevens-Johnson syndrome

Stevens-Johnson syndrome ( SJS ) is a severe blistering rash affecting both skin and mucous membranes. The majority of cases ...

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Transdermal Fentanyl: abuse in adolescents

Duragesic ( Fentanyl transdermal system ) has been marketed in Canada since 1992 and is indicated for the management of ...

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Duragesic: narcotic overdose and death

The Food and Drug Administration ( FDA ) issued a public health advisory to alert health care professionals, patients and ...

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Lipid helps cell wall protein fold into proper shape

Researchers at the University of Texas Medical School at Houston showed that phospholipids, which make up the permeable barrier of ...

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Natrecor, Advisory Panel provides recommendations

An Expert Panel, chaired by Eugene Braunwald, met on June 8th to review and assess important data associated with the ...

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Asthma, allergies may reduce risk of brain cancer

A study suggests having asthma, hay fever or another allergic condition may reduce the risk of developing one fatal form ...

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Autoimmune diseases, discovered how FTY720 controls T-cell traffic

Researchers have begun to clarify how one of the body's molecules controls the trafficking of T cells through the blood, ...

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Cell mutations that lead to apoptosis may contribute to aging in mammals

A study conducted at University of Florida has found that mutations in the mitochondria caused by obesity and lack of ...

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Diabetes, Ruboxistaurin may reduce risk of vision loss

Initial results of the Phase III clinical trial demonstrated that 32 milligrams per day of Ruboxistaurin (RBX) was well tolerated ...

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Brain size may depend upon how neural cells are cleaved

Researchers at Howard Hughes Medical Institute have discovered a novel way in which the brain size of developing mammals may ...

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Three deadly parasite genomes sequenced

Researchers have determined genetic blueprints for the parasites that cause three deadly insect-borne diseases: African sleeping sickness, leishmaniasis and Chagas ...

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Tarceva can prolong survival in patients with lung cancer

A trial, conducted by Canadian researchers, determined whether the epidermal growth factor receptor ( EGFR ) inhibitor Tarceva ( ...

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Multiple sclerosis, neural stem cells protect and repair brain tissues

Researchers at the San Raffaele Hospital in Milan ( Italy ) found adult mouse neural stem cells injected into the ...

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Microenvironment helps drive the breast cancer growth

Researchers at Dana-Farber Cancer Institute have discovered new evidence about how the "microenvironment" of breast cancers helps drive the cancers' ...

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Primate-to-human transmission of simian foamy virus

Researchers have identified the first reported case in Asia of primate-to-human transmission of simian foamy virus ( SFV ), a ...

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Role of neutrophils in the abdominal aortic aneurysm formation

Each year, 200,000 Americans find out that the largest blood vessel in their body, the aorta, may burst open at ...

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Genes associated with lung transplant rejection discovered

Researchers at the San Francisco VA Medical Center ( SFVAMC ) and the University of California, San Francisco ( UCSF ...

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Advanced lung cancer, Tarceva extends survival

A study, led by Canadian researchers, has demonstrated that Erlotinib ( Tarceva ) increases survival in patients with advanced non-small ...

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Sleeping beauty plays a significant role in identifying cancer genes

Researchers at the University of Minnesota Cancer Center and the National Cancer Institute ( NCI ), have discovered a new ...

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Higher mortality after heart attack in depressed patients with low heart rate variability

Physicians have known for years that depression increases the risk of dying in the months after a heart attack, but ...

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Estrogen, estrogen-like drugs may protect brain after stroke

Preliminary data suggest that estrogen or estrogen-like drugs not only help traumatized cells survive, they further enable post-stroke recovery by ...

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Heart failure quality of care variations found in US hospitals

Investigators at UCLA ( University of California, Los Angeles ) found large gaps and marked variation in U.S. hospitals' heart ...

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How to reverse a disease by targeting a combination of proteins

Researchers at the University of Wisconsin-Madison and the Cold Spring Harbor Laboratory, boosting levels of two critical proteins, that ...

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Excessive gambling behavior associated with dopamine agonist drugs

Researchers at Mayo Clinic showed a link between dopamine agonist drugs and pathological gambling. Habitual, compulsive gambling with losses up to ...

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Curcumin blocks growth of melanoma in lab test

Researchers from The University of Texas M. D. Anderson Cancer Center found curcumin, the pungent yellow spice found in both ...

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Molecule that inhibits regrowth of spinal nerve cells discovered

Researchers at University of Texas Southwestern Medical Center have found a molecule, that helps the body's motor nerve cells ...

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Children with congenital central hypoventilation syndrome show brain damage

Congenital central hypoventilation syndrome ( CCHS ) affects about 250 children in the United States, the genetic disease wreaks havoc ...

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Statins do not reduce risk of dementia

A study, led by University of Washington in Seattle, found the use of statins was not associated with a reduced ...

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Lorenzo's oil reduces risk of severe X-linked adrenoleukodystrophy

A study showed treatment of children with X-linked adrenoleukodystrophy ( ALD ) with Lorenzo's oil reduced their risk of ...

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Multiple sclerosis, a drug that inhibits IL12 could improve disease control

Researchers have found a chemical messenger that frees some white blood cells from the body's normal constraints, allowing the cells ...

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Perinatal strokes may lead to neurologic disorders

Four of five newborn infants who experience a stroke around the time of birth will develop neurologic disorders such as ...

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TACI gene mutations linked to immune deficiency syndromes

A gene mutation may account for many cases of immune deficiency, in particular two syndromes known as immunoglobulin A ( ...

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Diabesity: the fat connection

Researchers discovered how excess body fat can lead to the onset of diabetes. One out of 12 people in the western ...

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Weight loss drugs, the long-term health benefits remain unclear

A review of 22 studies suggests three commonly used drugs may help type 2 diabetes patients lose small amounts of ...

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Visual loss could be linked to impotence drugs

The Food and Drug Administration ( FDA ) has approved new labeling for Cialis ( Tadalafil ), Viagra ( ...

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Osteoarthritis of the knee, acupuncture offers short-term benefit

Results of a study suggest that acupuncture could reduce pain and improve joint functioning in the short-term for people with ...

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Certain types of exercise could protect against the risk of hip fracture

Certain types of exercise could protect against the steep increase in risk of hip fracture with age. The risk of hip ...

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Role of serotonin in modulating circadian rhythm

Researchers at the University of Pennsylvania School of Medicine have determined how serotonin decreases the body’s sensitivity to light and ...

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How cancer-preventing foods work

Researchers at the University of Illinois ( UIC ) at Chicago are unraveling the biochemical mechanism by which functional foods ...

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Anorexia nervosa, over-activity of dopamine receptors in the brain's basal ganglia

Researchers at the University of Pittsburgh found an over-activity of dopamine receptors in the brain's basal ganglia, an area known ...

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Safety of Cox-2 selective NSAIDs, report of the Expert Advisory Panel

Cox-2 selective inhibitors are used to relieve pain resulting from a variety of musculoskeletal disorders. Numerous studies have shown that their ...

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Oxidized lipids, predictors of coronary artery disease

By measuring specific oxidized phospholipid molecules in the blood, researchers led by University of California, San Diego ( UCSD ...

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Low-dose oral contraceptives may increase risk for heart attack or stroke

Researchers of the Virginia Commonwealth University ( VCU ) found women using low-dose oral contraceptives are at an increased risk ...

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Notch protein signaling directs early T-cell development

Researchers at the University of Pennsylvania School of Medicine have clarified the role of the Notch protein in T-cell development. In ...

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Postherpetic neuralgia, complications of Pregabalin withdrawal

Neurological complication may result from rapid withdrawal from Pregabalin ( Lyrica ). A report, published in the journal Annals of Neurology ...

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How Nipah virus infects cells

Researchers at the UCLA ( University of California - Los Angeles ) have discovered how the deadly Nipah virus infiltrates ...

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Sensory hyperreactivity patients may suffer from neurochemical alteration

Researchers have uncovered a link between patients with increased sensitivity to scents and chemicals, a condition known as sensory hyperreactivity ...

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Exercise can reduce high C-reactive protein levels

Inflammation in the body increases levels of a substance called C-reactive protein ( CRP ) in the blood. Many ...

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Androgen level is not predictive of low female sexual function

A study found no single androgen level is predictive of low female sexual function, and the majority of women with ...

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Aspirin and vitamin E for cancer prevention: no benefit

A growing body of literature has supported a protective effect of Aspirin and other nonsteroidal anti-inflammatory drugs ( NSAIDs ) ...

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Discovered gene linked to asthma susceptibility

Disruption of a single gene, Nrf2, plays a critical role in determining the susceptibility to asthma. Researchers led by Shyam Biswal, ...

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Schizophrenia, cognitive rehabilitation improves brain function

Memory study at the Washington University in St. Louis shows brain function in schizophrenia can improve with support. For ...

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Adult lifestyle biggest risk factor for diabetes

A team from the University of Newcastle upon Tyne, UK, studied 412 men and women and found that fatter adults ...

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Colorectal cancer, high acceptance of screening flexible sigmoidoscopy

The Prostate, Lung, Colorectal and Ovarian ( PLCO ) cancer screening trial is a randomized clinical trial to test ...

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Urine test helps detect aggressive vascular malformations

Vascular anomalies, caused by abnormal development of arteries, capillaries, veins or lymph vessels, can sometimes begin to progress, requiring aggressive ...

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Vitamin E does not prevent heart attack and stroke

New results from the Women's Health Study, a long-term clinical trial of the effect of vitamin E and Aspirin on ...

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Prostate cancer risk at all values of PSA

A study indicates there is no cutpoint of PSA with simultaneous high sensitivity and high specificity for monitoring healthy men ...

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CRX-675 Phase I clinical trial for patients with allergic rhinitis

Preliminary results of the clinical trial of CRX-675, a toll-like receptor 4 ( TLR4 ) agonist, in subjects allergic to ...

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