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Lifestyle critical for adult bone health

Fetal programming and childhood factors have been associated with serious adult health risks, such as obesity, heart disease, and cancer. The ...
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Lafora disease caused by mutations in the laforin gene

Researchers at UCSD ( University of California, San Diego ) found that Lafora disease, an inherited form of epilepsy that ...
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Low exposure to organochlorines, mercury affects thyroid status during pregnancy

Low levels of exposure to polychlorinated biphenyls ( PCBs ), certain pesticides, and mercury can interfere with thyroid hormone levels ...
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Wet age-related macular degeneration, Lucentis improves vision

A Phase III clinical trial of the drug Ranibizumab ( Lucentis ) met its primary efficacy endpoint of maintaining vision ...
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Dapoxetine developed to treat premature ejaculation

A Phase III clinical trial demonstrated that men taking Dapoxetine for the treatment of premature ejaculation ( PE ) ...
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Muse therapy following radical prostatectomy enhances penile recovery

A study evaluated the effects of the early use of Alprostadil ( Muse ) urethral suppository on erectile dysfunction ( ...
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Symbicort Single Inhaler Therapy gives greater improvement in asthma control than Seretide

Results from the COSMOS trial demonstrated that Symbicort Single Inhaler Therapy, ( Budesonide / Formoterol maintenance and reliever therapy ...
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Cannabinoid receptor blockers, new drugs for osteoporosis ?

Researchers at University of Aberdeen have made a finding that could pave the way for new drugs to treat osteoporosis ...
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Postmenopausal women who have undergone hysterectomy should not take Estrogen

The U.S. Preventive Services Task Force issued a new recommendation against the routine use of Estrogen to prevent chronic conditions ...
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Obesity is risk factor for aggressive prostate cancer

Obesity appears to increase the risk of prostate cancer, particularly aggressive form. Smaller prostates also increase the risk of aggressive disease. The ...
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Trospium, an incontinence drug, could have an additional topical effect on the bladder

A commonly prescribed incontinence drug may help patients in more than one way, according to research carried out at University ...
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Increased prevalence of coronary aneurysms among cocaine users

A study, published in Circulation - Journal of the American Heart Association - documented that cocaine predisposes to coronary ...
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Changes in brain receptors affect seizure and anxiety during the menstrual cycle

A study, carried out by researchers at University of California – Los Angeles ( UCLA ), showed that changes ...
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Type 2 diabetes, Muraglitazar decreases HA1c levels

Results from a Phase III study indicated that Muraglitazar, an investigational compound, significantly decreased hemoglobin A1c ( HA1c ) levels ...
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Insulin resistance, weight gain linked to premature aging

Tulane University researchers demonstrated that people with insulin resistance and weight gain also have prematurely shortened white blood cell telomeres ...
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High incidence of depression among heart attack patients

A report by HHS’ Agency for Healthcare Research and Quality ( AHRQ ) showed that one in five patients hospitalized ...
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Hormonal effect on psoriasis in pregnancy and post partum

High levels of estrogen correlated with improvement in psoriasis, whereas progesterone levels did not correlate with psoriatic change. The study investigated ...
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Disease progression model of pancreatic cancer developed

Researchers at the University of Pennsylvania - School of Medicine have developed an animal model of pancreatic cancer that closely ...
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Birth weight and breastfeeding may affect breast cancer risk

A research found that premenopausal women who were heavier than average at birth or had not been breastfed as infants ...
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Narcotic drugs effective for severe, chronic pain in elderly

Researchers at University of California San Francisco ( UCSF ) have compared younger versus older patients' desires / needs to escalate ...
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Tendency to hair loss inherited from the mother

It has long been suspected that hereditary factors are important in causing hair loss. However, up to now it was unclear ...
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Allergies increase risk for corneal transplant rejection

Corneal transplant patients who suffer from eye allergies are at a significantly higher risk of transplant failure than those without ...
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Interstitial cystitis biomarkers could lead to the first test and new therapies

Researchers at University of Pittsburgh have isolated two biomarkers for interstitial cystitis ( IC ). According to the National Institute of ...
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Natrecor, clinical trials show increased mortality

Scios and FDA notified HealthCare Professionals of revisions to the Adverse Reactions / Effect on Mortality section of the prescribing ...
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Canada: how to reduce the risk of West Nile Virus

Public Health Agency of Canada advised Canadians to take preventative measures to protect themselves from West Nile Virus. Despite a ...
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FDA warns against abuse of Dextromethorphan

FDA ( Food and Drug Administration ) is concerned about the abuse of Dextromethorphan ( DXM ), a synthetically ...
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Sodium Nitrite might be used to protect tissue after heart attack

Sodium Nitrite, a naturally occurring chemical and common meat preservative, is only used medically to treat cyanide poisoning. But if ...
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Infliximab shows efficacy in treatment of ulcerative colitis

Infliximab is the first biologic to show efficacy in two inflammatory bowel diseases ( IBD ), Crohn's Disease and ulcerative ...
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FDA approves Remicade for psoriatic arthritis

FDA ( Food and Drug Administration ) has approved Remicade ( Infliximab ) to reduce the signs and symptoms ...
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Panitumumab monotherapy for metastatic colorectal cancer

A Phase 2 study demonstrated that Panitumumab, a fully human monoclonal antibody directed against the epidermal growth factor receptor ...
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Dextromethorphan may help fibromyalgia patients

Dextromethorphan, an antitussive used to relieve a nonproductive cough caused by a cold, the flu, or other conditions, may help ...
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FDA Panel recommends approval for anti-HIV drug Tipranavir

FDA ( Food and Drug Administration ) Antiviral Drugs Advisory Committee recommended the approval of the anti-HIV drug Tipranavir ( ...
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Benefits of low dose Aspirin offset by risk in elderly

The benefits of giving low dose Aspirin to healthy individuals older than 70 to prevent cardiovascular disease are offset by ...
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Heart failure, FDA approves Atacand for use with an ACE Inhibitor

FDA ( Food and Drug Administration ) has approved a new use for angiotensin receptor blocker ( ARB ) Candesartan ...
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Parkinson’s, dietary vitamin E may have neuroprotective effect

A study evaluated the effect of vitamin C, vitamin E, and beta-carotene intake on the risk of Parkinson's disease ( ...
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Use of cellular telephones and brain tumour risk

Swedish study suggests that the use of a mobile phone in rural areas seems to increase the risk of developing ...
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Zelnorm shows promise in the treatment of upper gastrointestinal disorders

Zelnorm ( Tegaserod ) may offer new approach in the treatment of upper gastrointestinal ( GI ) disorders, such as ...
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Cervical cancer vaccine produces high anti-HPV immune response in adolescents

Gardasil is an investigational vaccine designed to prevent infection from four common human papillomavirus ( HPV ) types - 16, ...
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Asthma may double risk of invasive pneumococcal disease

Asthma is an independent risk factor for invasive pneumococcal disease. The risk among persons with asthma is at least double ...
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Lab abnormalities do not predict the risk of recurrence thrombotic event

Prothrombotic abnormalities do not appear to play an important role in the risk of a recurrent thrombotic event. Clinical factors ...
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Krabbe's disease, transplantation of umbilical-cord blood

Transplantation of umbilical-cord blood from unrelated donors in newborns with infantile Krabbe's disease favorably altered the natural history of the ...
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Colonoscopy, the best colon cancer screening tool for women

Researchers found that colonoscopy is the preferred colon cancer screening method in average-risk women because other screening tools would miss ...
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Timing of gluten exposure linked to celiac disease

Timing of introduction of gluten into the infant diet is associated with the appearance of celiac disease autoimmunity in children ...
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Breast cancer, serious complications linked to Doxorubicin-Docetaxel regimen

A clinical trial demonstrated that the chemotherapy regimen of Doxorubicin plus Docetaxel ( Taxotere ), used to treat breast cancer, ...
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Early stage colon cancer, exercise reduces risk of recurrence and death

Patients treated for early stage colon cancer fared significantly better if they exercised regularly at the level of an hour's ...
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Role for LINGO-1 in demyelinating diseases

Biogen Idec scientists have identified a molecule in the central nervous system ( CNS ) that may play a ...
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Enzastaurin in the treatment of recurrent glioblastoma multiforme

Preliminary results of a study showed patients with recurrent glioblastoma multiforme, a form of primary brain cancer, experienced a significant ...
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New treatment for recurrent glioblastoma multiforme

A " smart " drug treatment for a recurrent brain cancer slowed tumor growth in more than one-third of the ...
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Heredity and early fetal development linked to risk of autism

Research suggests that heredity and early fetal development play a causal role in autism. An analysis conducted by researchers at the ...
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Rifaximin for prevention of traveler's diarrhea

Rifaximin ( Xifaxan ), an oral, gastrointestinal-selective antibiotic, can be safely used to prevent attacks of travelers’ diarrhea caused by ...
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Rifaximin as a potential treatment option for Crohn's disease

A open-label study carried out by physicians at New York-Presbyterian Hospital / Weill Cornell Medical Center showed that there ...
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GERD linked to sleep disturbance

A survey of almost 2,000 people with gastroesophageal reflux disease ( GERD ) found that approximately half have trouble sleeping, ...
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New surgical options for obese patients

“ There has been a great deal of progress made in the development of safer, more effective obesity procedures,” said ...
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Biological therapies for inflammatory bowel diseases

IBD ( inflammatory bowel diseases ) is a term referring to several chronic diseases that cause inflammation of the intestines, ...
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Genetic factor in determining HIV/AIDS risk

People with more copies of a gene that helps to fight HIV are less likely to become infected with the ...
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Obesity linked to colorectal and esophageal cancers

Obesity appears to be associated with an increased risk of developing colorectal and esophageal cancers. Studies also show that losing weight ...
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Statins reduce risk of pancreatic and esophageal cancers

Statins, cholesterol-lowering drugs, are associated with a reduction in the risk of pancreatic and esophageal cancers. Statins are commonly used ...
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Acne drug does not increase depression in adolescents

A study showed that adolescents with moderate to severe acne taking Isotretinoin ( Accutane ) experience a reduction rather than ...
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Crohn’s disease, efficacy of the treatment with Adalimumab

A Phase III study showed that patients with moderate to severely active Crohn's disease treated with Adalimumab ( Humira ) ...
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SSRI antidepressants linked to increased GI bleeding

Use of SSRI antidepressants may increase gastrointestinal ( GI ) bleeding. A study suggests that the increase is similar to that ...
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Men with high blood pressure at risk for erectile dysfunction

Two separate studies found a link between hypertension and erectile dysfunction ( ED ). One of these studies also demonstrated ...
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Erbitux shows promise in cancer treatment

The results of several clinical studies of Cetuximab ( Erbitux ) have been presented at the American Society of Clinical ...
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Regular moderate exercise may reduce risk of ovarian cancer

A study carried out in Canada demonstrated that regular moderate recreational and work-related physical activity may reduce the risk of ...
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Aspirin may reduce risk of colon cancer recurrence and death

A study led by researchers at Dana-Farber found that Aspirin has a potential treatment benefit in people who have colon ...
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Antibody plus Docetaxel inhibits breast tumor growth

Researchers at University of Texas Southwestern Medical Center, Dallas, showed that a monoclonal antibody, that binds anionic phospholipids on tumor ...
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Rice bran oil may reduce cholesterol

Researchers from University of Rochester showed that total cholesterol levels in rats dropped by 42 percent, and LDL-cholesterol levels dropped ...
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Avastin plus chemotherapy improves survival in first-line non-squamous, non-small cell lung cancer

Data from a study ( E4599 ) of Bevacizumab ( Avastin ) plus Paclitaxel and Carboplatin in first-line non-squamous, ...
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Kidney cancer, Sorafenib doubles progression-free survival

Sorafenib demonstrated efficacy in an ongoing Phase III trial in patients with advanced renal cell carcinoma ( RCC ), or ...
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Zometa improves BMD in breast cancer patients receiving adjuvant therapy

Zoledronic Acid ( Zometa ), an intravenous bisphosphonate, was shown to inhibit aromatase inhibitor-induced bone loss in postmenopausal women treated ...
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Sutent extends overall survival in Gleevec-resistant GIST

An investigational new drug Sutent/SU11248 ( Sunitinib ) more than doubled survival and significantly reduced tumor growth and spread in ...
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Non-Hodgkin's lymphoma, earlier use of Bexxar may improve treatment outcomes

Treatment outcomes associated with the Bexxar therapeutic regimen ( Tositumomab and Iodine I 131 Tositumomab ) in non-Hodgkin's lymphoma patients ...
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Nicotine vaccine for smoking cessation shows promise

An experimental vaccine, called CYT002-NicQb, to treat nicotine addiction has achieved proof of efficacy.. CYT002-NicQb is a therapeutic vaccine in development ...
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Esomeprazole may reduce upper GI symptoms in patients using NSAIDs

Results from two clinical trials demonstrate that Esomeprazole ( Nexium ) can reduce upper gastrointestinal ( GI ) symptoms - ...
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Cellular defects in premature aging disease are reversible

Cells affected by Hutchinson-Gilford Progeria Syndrome ( HGPS ), a disease associated with premature aging, can be made healthy again, ...
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Efficacy of immunotherapy in advanced melanoma

Researchers, led by Steven A. Rosenberg, M.D., at the National Cancer Institute ( NCI ), part of the National Institutes ...
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New treatment guidelines for pregnant women with asthma

The National Asthma Education and Prevention Program (NAEPP) has issued the first new guidelines for managing asthma during pregnancy. The report ...
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Genetic cause of some Parkinson's disease cases identified

Two studies strongly suggest that a mutation in a recently discovered gene is the most common genetic cause of Parkinson’s ...
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SAHA in advanced, refractory cutaneous T-cell lymphoma

In a Phase II open label study with investigational oral SuberoylAnilide Hydroxamic Acid ( SAHA ), a new class of ...
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Depo-Provera, bone density appears to recover after adolescents discontinue use

Lower bone density appears to recover in adolescent females once they stop using the injected contraceptive depot Medroxyprogesterone acetate ( ...
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Rapid test developed for inherited immune deficiency

Researchers at the National Human Genome Research Institute ( NHGRI ), part of the National Institutes of Health ( NIH ...
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Tysabri plus Avonex reduces multiple sclerosis relapse rate

One-year data from the Phase III SENTINEL trial, presented at the 57th Annual Meeting - American Academy of Neurology ( ...
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Early breast cancer, Femara prolongs disease-free survival

The treatment with Letrozole ( Femara ) of postmenopausal women with early breast cancer prolonged disease-free survival by reducing the ...
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Tarceva plus chemotherapy improves survival in pancreatic cancer

A randomized study of Erlotinib ( Tarceva ) plus Gemcitabine met its primary endpoint by demonstrating a statistically significant 23.5 ...
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Revlimid, clinical benefits in patients with relapsed or refractory multiple myeloma

Initial clinical results from Pivotal Phase III Special Protocol Assessment ( SPA ) trials using Revlimid ( Lenalidomide ) as ...
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Multiple sclerosis: Tysabri reduces the risk of disability progression ( two-year data )

Two-year data from the AFFIRM Phase III monotherapy trial, presented at 57th annual American Academy of Neurology ( AAN ) ...
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Exercise may slow the development of Alzheimer’s

Physical activity seems to inhibit Alzheimer's-like brain changes in mice. The research demonstrated that long-term physical activity enhanced the learning ability ...
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Asthma, symptom-driven therapy may be sufficient for some adults

Some adults with mild persistent asthma may be able to adequately control their asthma by taking corticosteroids only when needed, ...
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Herceptin plus chemotherapy for early-stage breast cancer

A joint interim analysis of two studies of Trastuzumab ( Herceptin ) in early-stage breast cancer showed that HER2-positive breast ...
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Hypertension, ACE inhibitors work less well in black patients

Diuretics work better than newer therapies in treating high blood pressure and reducing risk of heart disease in both black ...
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Genome analysis reveals how leprosy spread

Leprosy, also called Hansen’s diasease, likely originated in East Africa and spread to Asia and Europe before being imported ...
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Avastin and Paclitaxel in first-line metastatic breast cancer

A study of Bevacizumab ( Avastin ) plus Paclitaxel chemotherapy in first-line metastatic breast cancer met its primary efficacy endpoint ...
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FDA approves Pegasys for the treatment of chronic hepatitis B

FDA ( Food and Drug Administration ) approved Pegasys ( Peginterferon alfa-2a ) for the treatment of chronic hepatitis B ...
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Use of insecticides linked to neurological symptoms for farmers

A research has showed that farmers who used agricultural insecticides experienced increased neurological symptoms, even when they were no longer ...
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Post traumatic stress disorder after traumatic events

The National Institute for Clinical Excellence ( NICE ) has issued guidelines for the NHS on how to improve the recognition, ...
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Prevention of secondary osteoporotic fractures in post menopausal women

The National Institute for Clinical Excellence ( NICE ) has issued guidance to the NHS in England and Wales on ...
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Diabetes drug Pioglitazone reduces carotid artery intima-media thickness

A study found that the diabetes drug Pioglitazone ( Actos ) reduced carotid artery intima-media thickness ( IMT ). Patients taking ...
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Minocycline may slow or prevent diabetic retinopathy

A study showed that Minocycline, a common antibiotic, may slow or prevent diabetic retinopathy. Researchers, from Pennsylvania State University College ...
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MRI-caused injuries in patients with implanted neurological stimulators

Serious injury or death can occur when patients with implanted neurological stimulators undergo MRI procedures. The FDA ( Food and Drug ...
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MMR vaccine does not increase the risk of Crohn's disease

MMR ( measles, mumps, and rubella ) vaccine does not seems to increase the risk of Crohn’s disease. It has been ...
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Vaccine prevents the development of prion disease in mice

Researchers at New York University ( NYU ) School of Medicine created the first active vaccine that can significantly delay ...
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