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Chemotherapy with Avastin increases risk of arterial thromboembolic events

Treatment with chemotherapy and Avastin ( Bevacizumab ), an anticancer drug, is associated with a greater risk of blood clots ...
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Obesity is associated with secondary hyperparathyroidism in men with moderate and severe chronic kidney disease

For patients with chronic kidney disease ( CKD ), the risk of elevated levels of parathyroid hormone ( PTH ), ...
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Dexmedetomidine, effective in counteracting Cocaine-induced symptoms

University of Texas ( UT ) Southwestern Medical Center researchers have discovered a treatment that counteracts the effects of Cocaine ...
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High-risk women: antioxidants show no clear benefit against cardiovascular events, death

Vitamins C and E and Beta-Carotene, either individually or in combination, do not appear to reduce the risk of cardiovascular ...
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FDA: Tasigna in treatment of Ph+ chronic myeloid leukaemia approved

The FDA ( Food and Drug Administration ) has approved Tasigna ( Nilotinib ) capsules for treatment of Philadelphia chromosome ...
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Advanced breast cancer: FDA has approved Ixempra

The FDA ( Food and Drug Administration ) has approved Ixempra ( Ixabepilone ), a new anti-cancer treatment, for use ...
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Rimonabant: safety issues

Rimonabant ( Acomplia / Zimulti ) is a cannabinoid receptor antagonist. It acts by blocking a specific type of receptor ...
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Provigil may cause serious rash e psychiatric symptoms

The FDA ( Food and Drug Administration ) and Cephalon notified healthcare professionals of updates to the Warnings section of ...
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Bacterial meningitis vaccine: FDA expands age range for use of Menactra

The FDA ( Food and Drug Administration ) has expanded the approved age range for Menactra, a bacterial meningitis vaccine, ...
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Trasylol appears to increase the risk for death compared to the other antifibrinolytic drugs

Data Safety Monitoring Board’s ( DSMB ) has recommended to stop patient enrollment in the Aprotinin ( marketed as Trasylol ...
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Obesity: contraindicated use of Sibutramine and cardiovascular adverse reactions

Sibutramine ( Meridia, Reductil ), a serotonin and norepinephrine reuptake inhibitor ( SNRI ), is an antiobesity agent marketed in ...
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Potential risk of sudden hearing loss with erectile dysfunction drugs

The FDA ( Food and Drug Administration ) has approved labeling changes for erectile dysfunction drugs in the class that ...
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Effectiveness of most post-traumatic stress disorder therapies is uncertain

Many people, including significant proportions of active duty military personnel and veterans, suffer from post-traumatic stress disorder ( PTSD ), ...
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Women with high or increasing blood pressure are up to three times more likely to develop diabetes

The Women’s Health Study has found that women who have high blood pressure levels are three times more likely to ...
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BHT-3009, a DNA vaccine against multiple sclerosis, appears safe, potentially beneficial

A newly developed DNA vaccine appears safe and may produce beneficial changes in the brains and immune systems of individuals ...
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Aclasta has received European approval as first once-yearly treatment for postmenopausal osteoporosis

Aclasta ( Zoledronic acid 5 mg ) has received European Union approval as the first once-yearly treatment for women with ...
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Severe plaque psoriasis: three subcutaneous doses of Ustekinumab resulted in long-term PASI 75 response

A study showed that more than two-thirds of patients with moderate to severe plaque psoriasis receiving two doses of Ustekinumab ...
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Treatment of premature ejaculation

Premature ejaculation is a frequent male sexual complaint that is mediated mainly by disturbances of serotonergic neurotransmission and certain serotonin ...
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Heart failure patients with atrial fibrillation: the importance of atrioventricular junction ablation in addition to cardiac resynchronisation therapy

Cardiac resynchronization therapy ( CRT ) is an effective therapy in symptomatic, drug-refractory heart failure ( HF ) patients with ...
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OPTIMIST study: PCI for stent thrombosis is associated with high rate of adverse clinical outcome

Stent thrombosis is a recognized complication occurring in 1-2% of patients with coronary artery disease treated by percutaneous coronary intervention ...
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getABI study excessive cardiovascular mortality in patients with peripheral arterial disease

Patients with atherosclerosis in the leg arteries face a substantially increased all-cause and cardiovascular mortality risk. The German epidemiological study on ...
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NICE: Rituximab and Adalimumab for the treatment of arthritis

The NICE ( National Institute for Health and Clinical Excellence ) has published final guidance on the use of Rituximab ...
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Haloperidol may cause QT prolongation and torsades de pointes

Johnson and Johnson and FDA( Food and Drug Administration ) informed Healthcare Professionals that the Warnings section of the ...
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Women with migraine with aura may have higher stroke risk

Women who have migraine headaches with visual symptoms ( or migraine with aura ) may be at increased risk for ...
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Verapamil for cluster headache may cause irregular heartbeats

A drug increasingly used to prevent cluster headache can cause heart problems, according to a study published in the Neurology. Those ...
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Study begins to reveal clues to the cause and progression of sepsis

Not all patients with sepsis mount the same immune response, even when they look the same clinically, according to findings ...
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DNA vaccine against multiple sclerosis: BHT-3009 appears safe, potentially beneficial

A newly developed DNA vaccine appears safe and may produce beneficial changes in the brains and immune systems of individuals ...
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Smoking may strongly increase long-term risk of age-related macular degeneration

Current and past smokers appear to have a higher risk of developing late age-related macular degeneration than those who have ...
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Pioglitazone appears to have overall favorable effect regarding risk of cardiovascular events

A meta-analysis of previous research suggests that use of Pioglitazone ( Actos ), a glycemic control medication for patients with ...
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FDA has approved second-generation smallpox vaccine

The FDA ( Food and Drug Administration ) has licensed a new vaccine to protect against smallpox, a highly contagious ...
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FDA: Evista for reducing the risk of invasive breast cancer in postmenopausal women

The FDA ( Food and Drug Administration ) approved Evista ( Raloxifene ) for reducing the risk of invasive breast ...
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Drug eluting stents should be used with caution in acute myocardial infarction

Drug-eluting stents ( DES ) are extremely effective devices to prevent restenosis following angioplasty. Yet, since last year, there is ...
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Aripiprazole reverses Haloperidol-induced hyperprolactinemia

Hyperprolactinemia and associated side effects often occur with antipsychotics. Researchers at Inje University, Republic of Korea, investigated the effect of ...
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Interstitial lung disease associated with Leflunomide

Leflunomide ( Arava ) is a disease-modifying anti-rheumatic drug ( DMARD ) for the treatment of rheumatoid arthritis, which has ...
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Tekturna, the first renin inhibitor for treating hypertension approved

The FDA ( Food and Drug Administration ) announced the approval of Tekturna ( Aliskiren ) tablets for the treatment ...
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ECG abnormalities associated with increased risk of death and cardiovascular events in women

Postmenopausal women without symptoms of cardiovascular problems who have minor or major abnormalities on an electrocardiogram ( ECG ) are ...
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Premenopausal women assigned to follow the Atkins diet for one year lost more weight

Premenopausal women who were assigned to follow the Atkins diet for one year lost more weight when compared to women ...
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Treatment of hospital-acquired pneumonia caused by methicillin-resistant Staphylococcus aureus

Nosocomial pneumonia and ventilator-assisted pneumonia may be polymicrobial and can be caused by a wide spectrum of pathogens. Potentially multidrug-resistant ...
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Growth hormone is not recommended as an antiaging therapy

Human growth hormone ( GH ), or Somatropin, is widely used as an antiaging therapy, although its use for this ...
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Risk of hepatotoxicity associated with Prexige

Prexige is a selective COX-2 inhibitor in the class of drugs called NSAIDs ( non-steroidal anti-inflammatory drugs ). In New Zealand, Novartis ...
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Peripheral neuropathy associated with Leflunomide

The purpose of the researchers at Université Victor Segalen, Bordeaux, France, has been to monitor the potential clinical neurotoxic symptoms in ...
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Risk of myocardial infarction associated with selective COX-2 inhibitors

Researchers at University of Manchester, UK, evaluated the risk of myocardial infarction associated with the use of selective cyclooxygenase-2 ( ...
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COREA-TAXUS trial: Celecoxib reduces restenosis after coronary angioplasty with a stent

The adjunctive use of Celecoxib ( Celebrex ) for 6 months after stent implantation in patients with coronary artery disease ...
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TGA: urgent advice regarding management of patients taking Lumiracoxib

As of 10 August 2007, the TGA ( Therapeutic Goods Administration ) had received eight reports of serious liver adverse ...
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Lung cancer: intravenous nanoparticle gene therapy shows activity

A cancer-suppressing gene has been successfully delivered into the tumors of stage 4 lung cancer patients via an intravenously administered ...
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TGA cancels registration of Prexige, an anti-inflammatory drug, because of serious liver side effects

The Therapeutic Goods Administration ( TGA ) has cancelled the registration of the osteoarthritis drug, Lumiracoxib because of serious liver ...
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Metabolic therapy prevents the development of multiple sclerosis, type 1 diabetes

A Glucosamine-like dietary supplement has been found to suppress the damaging autoimmune response seen in multiple sclerosis and type-1 diabetes ...
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Silent ischemia: angioplasty reduces long-term cardiac risk

When compared with intensive drug therapy, percutaneous coronary intervention ( PCI, angioplasty ) was more beneficial in reducing the long-term ...
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Safety and side effects of Gardasil

In a commentary published in the Canadian Medical Association Journal ( CMAJ ), Abby Lippman, an epidemiologist at McGill University ...
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Vascular dementia: efficacy and adverse effects of cholinesterase inhibitors and Memantine

A systematic review and meta-analysis evaluated the efficacy and safety of cholinesterase inhibitors and Memantine ( Ebixa, Namenda ) in ...
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Provenge improves survival in patients with androgen-independent prostate cancer

Active cellular immunotherapy is an approach that uses live human cells to re-engage the patient's own immune system. The goal ...
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Advanced breast cancer: immunologic and antitumor activity of Neuvenge

Dendreon announced publication of results from a Phase 1 study of Neuvenge, an investigational active cellular immunotherapy, in the Journal ...
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Safety alert: all patients should stop taking Lumiracoxib immediately

As of 10 August 2007, the TGA ( Therapeutic Goods Administration ), in Australia, had received eight reports of serious ...
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Heart failure risk: boxed warning for Pioglitazone and Rosiglitazone

The FDA ( Food and Drug Administration ) announced manufacturers, GlaxoSmithKline ( GSK ) and Takeda, of glitazones approved to ...
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Codeine use by nursing mothers may increase chance of serious side effects in infants

The FDA ( Food and Drug Administration ) is concerned that nursing infants may be at increased risk of Morphine ...
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Greater risk of Guillain-Barre syndrome reports when Gardasil is given with Menactra

The National Vaccine Information Center ( NVIC ) issued a new report on HPV vaccine ( Gardasil ) safety analyzing ...
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Garlic does not appear to lower cholesterol levels

Three forms of garlic, including raw garlic and two types of commercial garlic supplements, did not significantly reduce low-density lipoprotein ...
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Acetylsalicylic acid: long-term use associated with reduced risk of dying in women

Women who take low to moderate doses of Acetylsalicylic acid ( Aspirin) have a reduced risk of death from any ...
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Coenzyme Q10 does not improve Parkinson's disease symptoms

Small doses of the antioxidant coenzyme Q10 appear to increase blood levels of this naturally occurring compound in patients with ...
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HPV vaccine: questions and cautions

HPV infection is necessary for the development of cervical cancer and the vaccine may prevent primary infection with HPV types ...
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Osteonecrosis of the jaw linked to use of bisphosphonates

Most of the cases of osteonecrosis of the jaw are seen in oncology patients that, besides intravenous bisphosphonates, have received ...
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Molecular marker, microRNA, may help identify pancreatic cancer, and possibly predict survival time

Preliminary research suggests that the expression pattern of microRNA may be useful in differentiating between chronic pancreatitis and pancreatic cancer ...
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EN101 antisense reduces the severity of muscle weakness in myasthenia gravis

A new type of treatment significantly reduces the severity of muscle weakness in myasthenia gravis, giving hope for a new ...
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Young patients with leukaemia: lymphocyte count found to be a predictor of survival

One simple blood test could predict relapse or survival for children and young adults with acute leukemias, researchers from the ...
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Hepatitis C increases risk of non-Hodgkin lymphoma

Hepatitis C infection is associated with an increased risk of non-Hodgkin lymphoma of 20 percent to 30 percent, and a ...
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Human papillomavirus vaccine safety: VAERS reports 6 months after approval of Gardasil

On June 8th 2006, the FDA ( Food and Drug Administration ) announced the approval of Gardasil, and on June ...
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Recommendations on the use of Zometa in patients with malignancies

Bisphosphonates constitute a group of compounds and their structure is based on that of pyrophosphate:a compound that regulated precipitation and ...
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Zonisamide: no advantage in refractory partial epilepsy

Zonisamide ( Zonegran ) is a sulphonamide derivative that inhibits carbonic anhydrase; it resembles Topiramate ( Topamax ). The main clinical ...
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Risk factors for development of subclinical hypothyroidism during Valproate therapy

The purpose of the study by researchers from American University of Beirut Medical Center, Beirut, Lebanon, was to identify risk ...
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Management of osteonecrosis of the jaw in cancer patients treated with bisphosphonates

Cases of osteonecrosis of the jaw ( ONJ ) have been detected in cancer patients taking bisphosphonates as part of ...
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Guidelines for the management of patients with unstable angina and non-ST-elevation myocardial infarction revised

The American College of Cardiology ( ACC ) and the American Heart Association ( AHA ) have jointly released revised ...
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Liver stiffness indicates portal hypertension

Measuring liver stiffness using transient elastography can predict severe portal hypertension in patients with hepatitis C-related cirrhosis. As liver disease progresses, ...
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HCV patients survival after liver transplantation is not improving

For liver transplant recipients without hepatitis C ( HCV ), survival has improved over time. However, for recipients with HCV, ...
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Heart transplant: Sirolimus improves kidney function

A new immunosuppression regimen for heart transplant patients can improve kidney function and prevent transplant coronary artery disease, according to ...
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Rosiglitazone seems to be associated with risk of myocardial infarction and death from cardiovascular causes

Rosiglitazone ( Avandia ) is widely used to treat patients with type 2 diabetes mellitus, but its effect on cardiovascular ...
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Lavender and tea tree oils may cause breast growth in boys

A study published in the the New England Journal of Medicine ( NEJM ) suggests that repeated topical use of ...
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GVHD in stem-cell patients: a reformulation of Beclomethasone reduces mortality

Gastrointestinal graft-versus-host disease is a common and potentially deadly side effect for patients who undergo an allogeneic stem-cell transplant to ...
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Citalopram effective in treating depression in patients with coronary artery disease

Patients with symptoms of depression who have coronary artery disease showed improvement of their symptoms with use of the drug ...
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Low-dose steroids reduce joint damage from rheumatoid arthritis

Low doses of steroids can inhibit joint damage when used in the early phase of rheumatoid arthritis, according to a ...
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Diuretics not recommended for preventing preeclampsia

Although they were prescribed widely in the 1960s to women looking to avoid dangerously high blood pressure during pregnancy, diuretic ...
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Exercise has no effect on risk of knee osteoarthritis

Regular exercise is recommended for middle-aged and older people, but the effect of exercise on the development of osteoarthritis in ...
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Women in polluted areas at higher risk of cardiovascular disease

Women living in areas with higher levels of air pollution have a greater risk of developing cardiovascular disease and subsequently ...
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Increased incidence of grade IIIA acute rejection in heart transplant patients switched from calcineurin inhibitor and CellCept to Rapamune and CellCept at 12 weeks post heart transplantation

Roche Laboratories, following discussion with the FDA ( Food and Drug Administration ), informed Health Care Professionals of important safety ...
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Folic acid cuts risk of cleft lip

Taking Folic acid supplements in early pregnancy seems to substantially reduce the risk of cleft lip. It is widely known that ...
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Trichomoniasis associated with increased risk for HIV infection

A study has shown a significantly increased risk of HIV infection among women with a common sexually transmitted disease, trichomoniasis. ...
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Men with breast cancer face high risk of second cancer

Men who have been treated for breast cancer face a significantly high risk of getting cancer once again, according to ...
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Risperidone controls some symptoms in autism disorder

Risperidone ( Risperdal ), a drug used to control schizophrenia symptoms, may also help treat behaviors found in autism spectrum ...
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Advanced breast cancer in postmenopausal women: aromatase inhibitors associated with increase in survival

Aromatase inhibitors, a type of hormone therapy used to treat advanced breast cancer in postmenopausal women, result in a small ...
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Predicting the risk of rheumatoid arthritis for early arthritis patients

Marked by chronic inflammation of the joints and tissue, rheumatoid arthritis is a painful and potentially disabling autoimmune disease. A ...
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Spondylarthritis: the process of ankylosis could become a separate therapeutic target

Any form of arthritis that affects one or more vertebral joints, spondylarthritis ( SpA ) represents a group of closely ...
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Young people who died suddenly and inexplicably had genetic heart defects

In 49 young people who died suddenly and inexplicably at an average age of 14, conventional autopsies found no cause ...
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Selenium supplements may contribute to reduced HIV viral load

Taking daily Selenium supplements appears to increase the level of the essential mineral in the blood and may suppress the ...
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Daily use of antidepressants associated with increased risk of fracture in older adults

Daily use of the antidepressant medications known as selective serotonin reuptake inhibitors ( SSRIs ) by adults 50 years and ...
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Long-term narcotics use for back pain may be ineffective and lead to abuse

Narcotic drugs ( opioids ) are commonly prescribed for short-term relief of chronic back pain, but their effectiveness long-term has ...
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Periodontal disease associated with increased risk of pancreatic cancer

Pancreatic cancer is an extremely difficult disease to treat and little is known about what causes it. One established risk ...
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Risk of death increases with combined heart and stroke prevention surgery

Patients who undergo combined heart bypass surgery and carotid endarterectomy, the most commonly used stroke prevention surgery, significantly increase their ...
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Low-dose Aspirin reduces the risk of asthma

In a large, randomized, placebo-controlled study of 22,071 healthy male physicians, taking a low-dose of Aspirin every other day lowered ...
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Dual gene therapy suppresses lung cancer in preclinical test

Combination gene therapy delivered in lipid-based nanoparticles drastically reduces the number and size of human non-small cell lung cancer tumors ...
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Lymphocyte-white blood cell count ratio can help distinguish between mononucleosis and tonsillitis

Measuring a patient's ratio of white blood cell types may help physicians accurately distinguish between the similar conditions infectious mononucleosis ...
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Benzodiazepines are not associated with hip fractures

Benzodiazepine use was not shown to be associated with hip fractures after all, according to a new study from Harvard ...
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