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Switching from twice-daily Combivir to once-daily Truvada in patients with HIV ( preliminary 24-week data )

Preliminary 24-week data from the COMET ( Combination of Efavirenz and Truvada ) study were presented at the 10th European ...
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Hypoglycemia may complicate gastric bypass surgery

A study by collaborating researchers at Joslin Diabetes Center, Beth Israel Deaconess Medical Center ( BIDMC ), and Brigham and ...
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No connection between increased belly fat and decreased limb fat in men who take antiretrovirals

A study by researchers at the San Francisco VA Medical Center and the University of California, San Francisco did find ...
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Buprenorphine appears effective in treating teen heroin addiction

In a comparison of two drugs prescribed to treat teenagers dependent on heroin and other opioids, the drug Buprenorphine was ...
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Amoxicillin use during infancy may be linked to tooth enamel defects

Use of the antibiotic Amoxicillin during infancy appears to be linked to tooth enamel defects in permanent teeth. The study is ...
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CREB, a brain protein, linked to alcoholism and anxiety

Researchers at the University of Illinois at Chicago have discovered that a protein found in the brain is genetically linked ...
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Blood cell defect linked to pulmonary hypertension

Howard Hughes Medical Institute researchers at Duke University Medical Center have found that a persistent scarcity of oxygen in body ...
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Stratifin gene defect leading to abnormal skin development and cancer identified

Researchers at Jefferson Medical College and at the Wadsworth Center in New York have identified a gene defect in mice ...
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A novel type of T helper cells found to be a key to inflammatory diseases

The molecular roots of inflammatory and autoimmune diseases such as asthma, arthritis, and multiple sclerosis ( MS ) have been ...
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Herceptin and early breast cancer: available evidence is insufficient to make reliable judgments

Intense debate surrounds the use of Herceptin for early breast cancer. Promising results were initially presented at the American Society ...
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HIV infection rates decreasing in several countries

According to UNAIDS/WHO report, there is new evidence that adult HIV infection rates have decreased in certain countries and that ...
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Potential health risk associated with Chinese medicine Shortclean

Health Canada is warning consumers not to take the Chinese medicine Shortclean because it contains Glibenclamide ( Glyburide ) and ...
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Exercise in midlife could reduce the risk of dementia and Alzheimers’s disease

Being physically active in midlife could decrease a person’s risk of dementia and Alzheimer’s disease ( AD ) later in ...
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Bocavirus causes respiratory tract infections in children

Researchers at Karolinska Institutet have discovered a previously unknown virus that has been found to affect children. The virus, called ...
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Two cases of alleged suicide associated with Tamiflu

Tamiflu ( Oseltamivir ) is an antiviral approved in the European Union for the treatment of influenza in children between ...
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Role of thyroid hormone in brain development and behavior

A study, led by Bjorn Vennstrom at the Karolinska Institute ( Sweden ), has identified novel neural functions of thyroid ...
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No evidence Tamiflu linked to deaths in Japan

Based on the information available, FDA’s Pediatric Advisory Committee ( PAC ) can not conclude that there is a causal ...
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Long-acting beta 2-adrenergic agonists may make asthma episodes more severe

The FDA ( U.S. Food and Drug Administration ) requested manufacturers of Advair Diskus ( Fluticasone propionate & Salmeterol inhalation ...
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Substituting carbohydrates in diet with protein or unsaturated fats may reduce cardiovascular risk

A study found that partially substituting protein and monounsaturated fat for carbohydrates can improve cholesterol levels, further lower blood pressure ...
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Model identifies genes that induce normal skin cells to become aggressive cancer cells

Researchers at Northwestern University have developed a novel, three-dimensional model that allows scientists to observe how interacting with the microenvironment ...
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Chronic stress accelerates atherosclerosis following angioplasty procedure

A research performed in animal studies at Georgetown University Medical Center showed that chronic stress can induce rapid blocking of ...
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Rheumatic disease increases risks in pregnancy

Women with rheumatic disease experience greater pregnancy risks and longer hospital stays than the average pregnant woman. The findings from the ...
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Acute myeloid leukemia, ERG may play a key role in leukemia development

Researchers have discovered a new marker that might identify a serious form of acute myeloid leukemia ( AML ) in ...
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Treatment of pancreatic carcinoma by adenoviral mediated gene transfer of vasostatin in mice

A gene responsible for the production of a protein called vasostatin may prove a promising new way of treating pancreatic ...
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Children with neurological and neuromuscular diseases at risk for flu-related respiratory failure

Children with neurological and neuromuscular diseases should receive an annual influenza vaccination because of a higher risk of respiratory failure ...
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Dendritic cell-based therapy uses tumor cells and danger signals to stimulate tumor immunity

A new type of immunotherapy in which dendritic cells are tricked into action against cancer when they are exposed to ...
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Gamma-linolenic acid inhibits action of Her-2/neu, responsible for some breast cancers

Gamma-linolenic acid ( GLA ), a substance in evening primrose oil and several other plant oils used in herbal medicine, ...
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Testicular carcinoma, fatherhood possible for many cancer survivors

The overall rate of fatherhood after treatment for testicular cancer is high, but the ability to conceive and the time ...
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TAP protein suppresses prostate cancer, enhances effects of vitamin E

Researchers have identified a protein that disrupts an important signaling pathway in prostate cancer cells and suppresses growth of the ...
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Calcitriol and QW-1624-F2-2 are promising for prevention of androgen-dependent prostate cancer progression

A study presented at the American Association for Cancer Research's 4th annual Frontiers in Cancer Prevention Research meeting in Baltimore, ...
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High doses of Ibuprofen cause significant gastrointestinal bleeding

People who take high doses of Ibuprofen on a regular basis are three times more likely to experience gastrointestinal ( ...
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FAK, an enzyme, could play a major role in promoting aggressive melanoma

Researchers at Northwestern University have discovered a key signaling mechanism that may promote the ability of highly aggressive malignant melanoma ...
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Undiscovered protein may help identify patients at risk for type 1 diabetes

Researchers have discovered a combination of tests that can more accurately predict who will develop type 1 diabetes. In the ...
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INS2, a natural carbohydrate, can help lower blood sugar

A research carried out by a team of experts at the University of Virginia Health System found that a carbohydrate ...
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Protein aggregates in Lou Gehrig's disease linked to neuron death

French neurologist Jean-Martin Charcot first described amyotrophic lateral sclerosis ( ALS ) in 1869, but, nearly 140 years later, little ...
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Depression linked to higher death rate for people with type 2 diabetes

Type 2 diabetes and depression can be a fatal mix. Patients whose type 2 diabetes was accompanied by minor or ...
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Bone marrow stem cells may heal hearts even years after heart attacks

A study, published in the Journal of the American College of Cardiology, showed that left ventricular function and exercise capacity ...
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Growth patterns into childhood reveal risk of coronary heart disease later in life

The risk of developing coronary heart disease as an adult is more strongly related to childhood growth patterns than body ...
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Wnt signaling controls the fate of stem cells in adult brains

Researchers at the Salk Institute for Biological Studies have identified a crucial cellular signal that controls the fate of stem ...
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Decline in breast cancer deaths explained by use of screening and adjuvant

Early detection through screening mammography and improved adjuvant treatment have contributed almost equally to the substantial decrease in breast cancer ...
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Invasive aspergillosis survival, Voriconazole may be better than Amphotericin B

The retrospective analysis, published in the Clinical Infectious Diseases, showed that patients who initially received antifungal agent Vfend ( Voriconazole ...
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Depression raises disability risk, especially among African-Americans

A study found that depressed middle-aged adults are at four times greater risk for being unable to perform everyday tasks ...
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Breastfeeding may protect against gluten intolerance

Breastfeeding may protect children against gluten intolerance otherwise known as coeliac disease, suggests research published in the Archives of Disease ...
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Multiple myeloma: NPI-0052, a compound from marine bacteria, appears effective

An anti-cancer compound derived from bacteria dwelling in ocean-bottom sediments appears in laboratory tests to be a potent killer of ...
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PET imaging applied to immune system

br>In a series of experiments with genetically engineered mice, a team of researchers from the Howard Hughes Medical Institute ( ...
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Cardiospheres-derived cells can repair heart attack damage

Stem cells derived from human heart tissue develop into multicellular, spherical structures called cardiospheres that express the normal properties of ...
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Exercise plus gene therapy shows promise for treating amyotrophic lateral sclerosis

A study in mice gives hope that a combination of gene therapy and exercise may extend the lives of people ...
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Fentanyl patch alternative to oral opioids for pediatric pain patients

Fentanyl transdermal patch ( Duragesic ) may be an effective way to control pain in children. Results from an international study ...
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DC-SIGN has an important function in amplifying tuberculosis infection in the lung

Tuberculosis is the most common major infectious disease. It is estimated that two billion people--or one-third of the world's population -- ...
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Cancer-associated muscle wasting and muscular dystrophy share dystrophin dysfunction

A study provides important insight into the mechanisms of a muscle wasting disorder that interferes with treatment for cancer and ...
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Chronic myelogenous leukaemia, Forskolin may be effective in Imatinib-resistant patients

Researchers have identified a new pathway in the progression of chronic myelogenous leukemia ( CML ). They also discovered that ...
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Physical activity improves life expectancy and cardiovascular health

People age 50 and older who engage in moderate or high levels of physical activity live longer and have less ...
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Walking produces improvements in cardiorespiratory fitness

Exercise counseling with a prescription for walking at either hard intensity or high frequency produces improvements in cardiorespiratory fitness. The study ...
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Two biomarker in stroke survivors may provide predictive information for recurrent ischemic stroke

A study, published in the Archives of Neurology, showed that measurement of two biomarker levels in stroke survivors may provide ...
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CDT test cuts care costs for chronically ill patients

A health economics analysis found that adding a new alcohol biomarker test to patients' revelations about their drinking habits could ...
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Genetic variations reduce the ability of statin to lower LDL cholesterol

Researchers reported at the American Heart Association's Scientific Sessions 2005 that a newly discovered genetic variation, in combination with a ...
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NF-kB signaling pathway may determine life or death for damaged brain cells

Researchers at the Universities of Heidelberg and Ulm and a unit of the European Molecular Biology Laboratory ( EMBL ) ...
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Celecoxib and Rofecoxib: higher risk of death after heart attack

A study, reported at the American Heart Association's Scientific Sessions 2005, showed that taking either COX-2 inhibitors or other ...
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Ketogenic diet prevents seizures by enhancing brain energy production, increasing neuron stability

Although the high-fat, calorie-restricted ketogenic diet ( KD ) has long been used to prevent childhood epileptic seizures that are ...
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Sativex, a cannabis-based medicine, reduces central neuropathic pain in patients with multiple sclerosis

A UK study, published in the journal Neurology, showed that the cannabis based medicine, Sativex, is effective in reducing ...
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Obestatin is a new hormone that suppresses appetite

The finding, published in the Science, offers a key to researchers developing treatments for obesity. Researchers at the Stanford University ...
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Statins reduce the risk of stroke and death after carotid artery surgery

Carotid artery endarterectomy ( CEA ) is the most commonly performed operation to prevent stroke in the United States. However, the ...
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High accuracy of a new non-invasive screening for Down syndrome

A study of more than 38,000 pregnant women at 15 U.S. centers demonstrated the high accuracy of non-invasive screening for ...
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Tranilast boosts immune system in a murine model of multiple sclerosis

A study, published in the journal Science, breaks new ground on the effects of tryptophan — an amino acid found ...
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RTS,S malaria vaccine protects children for at least 18 months

New data on the duration of efficacy of GlaxoSmithKline’ malaria vaccine candidate, RTS,S/AS02A, in children showed that vaccine remains efficacious ...
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Human papillomavirus vaccine: AS04 adjuvant offers stronger immune response for longer duration

An investigational human papillomavirus ( HPV ) 16/18 L1 vaccine formulated with an innovative adjuvant, AS04, induced a stronger immune ...
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Ortho Evra contraceptive patch exposes women to higher levels of estrogen than most birth control pills

FDA ( Food and Drug Administration ) approved updated labeling for the Ortho Evra contraceptive patch to warn healthcare ...
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Lucentis maintains or improves vision in 95 percent of patients with age-related macular degeneration ( preliminary data )

A second Phase III clinical study of the investigational drug Lucentis ( Ranibizumab ) met its one-year primary efficacy endpoint ...
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Osteoarthritis, Chondroitin sulfate and Glucosamine may be an effective combination in reducing knee pain

A research presented at the American College of Rheumatology Annual Scientific Meeting in San Diego, California, showed that Glucosamine and ...
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TORC2 protein, a key regulator of blood glucose levels

Researchers at the Salk Institute for Biological Studies then reported the discovery of a key cellular switch that instructs the ...
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Sleep apnea and death association point to need to examine treatments

Two studies, published in the New England Journal of Medicine, draw attention to the newly recognized association between sleep disorders ...
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Glioblastoma, screening for two gene variations can predict which tumors will respond to a specific class of drugs

A study showed that screening glioblastoma brain tumors for two gene variations can reliably predict which tumors will respond to ...
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Gene therapy to restore alveoli and lung capillaries in damaged rat lungs

Researchers at the University of Alberta pioneer gene therapy to restore alveoli and lung capillaries in damaged rat lungs; first ...
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Children of bipolar parents score higher on creativity test

Researchers at the Stanford University School of Medicine have shown for the first time that a sample of children who ...
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Irritable bowel syndrome may be caused by bacterial overgrowth in the gut

Researchers at Cedars-Sinai Medical Center have found that a nonabsorbable antibiotic – one that stays in the gut – may ...
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The first steps in transcription-coupled repair linked to premature aging discovered

A team of scientists led by Priscilla Cooper, a senior staff scientist in the Life Sciences Division of the Department ...
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PET imaging with FDG to determine the extent of spread of cancers of the reproductive system in women

The use of positron emission tomography ( PET ) with the radiotracer fluorodeoxyglucose ( FDG ) is “underutilized” in diagnosing ...
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Quaking gene suppresses tumor growth by inhibiting production of a protein associated with GLI1, a oncogene

The Quaking gene, first described as a mutation in mice that causes rapid tremor, is thought to suppress tumor formation ...
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Rheumatoid arthritis, cannabis-based medicine relieves the pain and suppresses the disease

A study has found that cannabis-based medicine ( CBM ) for treating rheumatoid arthritis has a significant effect on easing ...
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Vitamin D status appears more important than high calcium intake for maintaining calcium metabolism

A study, published in the JAMA, has discovered that calcium intake levels of more than 800 mg/day may be unnecessary ...
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Acute pharyngitis, physicians overprescribe antibiotics for children

A study, published in the journal JAMA, showed that physicians prescribe antibiotics for more than half of children with sore ...
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No link found between development of hypertension and caffeine intake in women

A study, published in the journal JAMA, has found that habitual coffee drinking is not associated with an increased risk ...
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Effects of light on the adrenal glands

A report, published in the journal Cell Metabolism, has found powerful effects of light on the adrenal glands, a ...
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A novel link connecting macronutrients in the diet to hunger discovered

Researchers have discovered new evidence to explain the observation that diets rich in protein stunt the appetite. The findings, published in ...
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Atherosclerosis is linked to inherent inability to repair vascular damage

Researchers at the Duke University Medical Center have demonstrated that the progression of the artery-clogging disease atherosclerosis is linked to ...
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Link between maternal malaria, pregnancy history, and infant risk

Every year at least 30 million women in malaria-endemic areas of Africa become pregnant. Many of them develop placental malaria, ...
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Malaria risk: genetic factors account for about one quarter to one third

Humans exposed to malaria get infected and sick to varying degrees, and some of that variation is due to differences ...
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Malaria vaccine shows promise in early clinical trial

Pierre Druilhe and colleagues, from the Institut Pasteur in Paris, have completed the first human trial of a malaria vaccine ...
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Link between prolonged bottle-feeding and iron deficiency

A study by Medical College of Wisconsin and Children's Hospital of Wisconsin researchers has shown that children bottle-fed past 12 ...
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Advertisements for SSRI antidepressants are misleading

Consumer advertisements for a class of antidepressants called SSRIs often claim that depression is due to a chemical imbalance in ...
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Flu chip may determine the genetic signatures of specific influenza strains from patient samples within hours

A " Flu Chip " has been developed at the University of Colorado at Boulder that can determine the genetic ...
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Mutations in the BRAF gene predict sensitivity to MEK inhibitors

Researchers, led by scientists at Memorial Sloan-Kettering Cancer Center, have discovered that a new class of drugs -- now in ...
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Eating behavior: dangers of mixing stress, deprivation and tempting foods

Two studies, published in the Behavioral Neuroscience, showed that when animals are stressed, deprived and exposed to tempting food, they ...
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Rheumatoid arthritis, cytokines have both pro- and anti-inflammatory responses

Using a humanized mouse model that mimics the effects of human rheumatoid arthritis ( RA ), researchers have discovered that ...
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Estrogens in soy does not increase the risk of uterine cancer in postmenopausal women

Studies in monkeys and women suggest that a diet high in the natural plant estrogens found in soy does not ...
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High incidence of sinusitis in patients with chronic cough

Researchers at Mayo Clinic found that more than one-third of chronic cough patients given a CT scan had sinusitis, inflammation ...
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Nicotine vaccine: a promising treatment for nicotine addiction

To combat cigarette smoking, researchers are seeking ways to combat the habit which affects more than 45 million Americans. One new ...
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Plant extract may protect against liver cancer

A study has shown that a synthetic version of a plant extract prevents mold toxin-induced liver cancer in rats. The extract, ...
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Broccoli sprouts can improve chronic bacterial gastritis

Researchers in Japan and Baltimore have found that a daily serving of broccoli sprouts can improve chronic bacterial gastritis, a ...
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Waist-to-hip ratio better than BMI for assessing risk of heart attack

A study, published in The Lancet, has shown that waist-to-hip ratio, not body mass index ( BMI ), is the ...
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